Pattison J R, Dane D S
J Hyg (Lond). 1975 Aug;75(1):91-8. doi: 10.1017/s0022172400047100.
The results of testing sera from 111 patients with rubella-like illnesses and 283 contacts of patients with rubella-like illnesses are described. A sensitive haemagglutination-inhibition test was used in conjunction with fractionation of serum proteins when this was indicated. It was concluded that the testing of serum protein fractions for IgM and IgG rubella antibody greatly increased the effectiveness of laboratory diagnosis. Evidence is presented that during the study period subclinical rubella was relatively uncommon in adults and that the accuracy of clinical diagnosis was high.
本文描述了对111例风疹样疾病患者的血清以及283例风疹样疾病患者接触者的血清检测结果。在必要时,采用了灵敏的血凝抑制试验并结合血清蛋白分级分离法。得出的结论是,检测血清蛋白组分中的IgM和IgG风疹抗体可大大提高实验室诊断的有效性。有证据表明,在研究期间,亚临床风疹在成人中相对少见,且临床诊断的准确性较高。