人干扰素的无细胞合成
Cell-free synthesis of human interferon.
作者信息
Pestka S, McInnes J, Havell E A, Vilcek J
出版信息
Proc Natl Acad Sci U S A. 1975 Oct;72(10):3898-901. doi: 10.1073/pnas.72.10.3898.
Abstract
With mRNA prepared from induced human fibroblasts biologically active human interferon was synthesized de novo in a cell-free extract from mouse cells. The identity of the antiviral activity as human interferon was demonstrated by its species and antigenic specificity.
摘要
用从诱导的人成纤维细胞制备的信使核糖核酸（mRNA），在小鼠细胞的无细胞提取物中重新合成了具有生物活性的人干扰素。通过其种属和抗原特异性证明了这种抗病毒活性为人干扰素。
相似文献
1
Cell-free synthesis of human interferon.人干扰素的无细胞合成
Proc Natl Acad Sci U S A. 1975 Oct;72(10):3898-901. doi: 10.1073/pnas.72.10.3898.
2
De novo cell-free synthesis of human interferon.人干扰素的无细胞从头合成。
Ann N Y Acad Sci. 1977 Mar 4;284:697-702. doi: 10.1111/j.1749-6632.1977.tb22005.x.
3
Relationship between interferon production and interferon messenger RNA synthesis in human fibroblasts.人成纤维细胞中干扰素产生与干扰素信使核糖核酸合成之间的关系。
Proc Natl Acad Sci U S A. 1977 Apr;74(4):1483-7. doi: 10.1073/pnas.74.4.1483.
4
Synthesis of interferon in heterologous cells, cell-free extracts, and Xenopus laevis oocytes.干扰素在异源细胞、无细胞提取物及非洲爪蟾卵母细胞中的合成。
Tex Rep Biol Med. 1977;35:117-25.
5
[Superinduction of interferon and and a study of its messenger RNA].[干扰素的超诱导及其信使核糖核酸的研究]
Antibiotiki. 1977 Mar;22(3):247-52.
6
Correlation between the induction of mouse interferon and the amount of its mRNA.小鼠干扰素的诱导与其mRNA量之间的相关性。
Eur J Biochem. 1979 Jul;98(1):215-21. doi: 10.1111/j.1432-1033.1979.tb13179.x.
7
Relative quantitative assay of the biological activity of interferon messenger ribonucleic acid.干扰素信使核糖核酸生物活性的相对定量测定
J Gen Virol. 1975 May;27(2):225-38. doi: 10.1099/0022-1317-27-2-225.
8
Interferon messenger RNA: translation in heterologous cells.干扰素信使核糖核酸：在异源细胞中的翻译
Proc Natl Acad Sci U S A. 1972 May;69(5):1203-7. doi: 10.1073/pnas.69.5.1203.
9
Intracellular location of human fibroblast interferon messenger RNA.人成纤维细胞干扰素信使核糖核酸的细胞内定位
Biochem Biophys Res Commun. 1978 Jun 29;82(4):1300-5. doi: 10.1016/0006-291x(78)90329-7.
10
Interferon messenger RNA content of human fibroblasts during induction, shutoff, and superinduction of interferon production.人成纤维细胞在干扰素产生的诱导、关闭和超诱导过程中的干扰素信使核糖核酸含量。
Proc Natl Acad Sci U S A. 1977 Aug;74(8):3409-13. doi: 10.1073/pnas.74.8.3409.
引用本文的文献
1
Partial characterization of gamma (immune) interferon mRNA extracted from human lymphocytes.从人淋巴细胞中提取的γ（免疫）干扰素信使核糖核酸的部分特性分析
Proc Natl Acad Sci U S A. 1981 Jun;78(6):3469-72. doi: 10.1073/pnas.78.6.3469.
2
The interferon renaissance: molecular aspects of induction and action.干扰素的复兴：诱导与作用的分子层面
Microbiol Rev. 1981 Jun;45(2):244-66. doi: 10.1128/mr.45.2.244-266.1981.
3
Le interferon mRNA from human fibroblasts.来自人成纤维细胞的γ干扰素信使核糖核酸。
Proc Natl Acad Sci U S A. 1980 Sep;77(9):5341-5. doi: 10.1073/pnas.77.9.5341.
4
Synthesis of human fibroblast interferon by E. coli.大肠杆菌合成人成纤维细胞干扰素。
Nucleic Acids Res. 1980 Sep 25;8(18):4057-74. doi: 10.1093/nar/8.18.4057.
5
An evaluation of messenger RNA competition in the shutoff of human interferon production.对人类干扰素产生关闭过程中信使核糖核酸竞争的评估。
Proc Natl Acad Sci U S A. 1976 May;73(5):1621-5. doi: 10.1073/pnas.73.5.1621.
6
Interferons: anti-neoplastic drugs?干扰素：抗肿瘤药物？
Blut. 1977 Sep 18;35(4):277-88. doi: 10.1007/BF00996140.
7
Biological detection of specific mRNA molecules by microinjection.通过显微注射对特定信使核糖核酸分子进行生物学检测。
Proc Natl Acad Sci U S A. 1979 Sep;76(9):4503-6. doi: 10.1073/pnas.76.9.4503.
8
Induction and decay of human fibroblast interferon mRNA.人成纤维细胞干扰素mRNA的诱导与衰减
Proc Natl Acad Sci U S A. 1977 Oct;74(10):4415-9. doi: 10.1073/pnas.74.10.4415.
9
Interferon messenger RNA content of human fibroblasts during induction, shutoff, and superinduction of interferon production.人成纤维细胞在干扰素产生的诱导、关闭和超诱导过程中的干扰素信使核糖核酸含量。
Proc Natl Acad Sci U S A. 1977 Aug;74(8):3409-13. doi: 10.1073/pnas.74.8.3409.
10
Enucleation and reconstruction of interferon-producing cells.干扰素产生细胞的摘除与重建
Proc Natl Acad Sci U S A. 1977 Aug;74(8):3391-5. doi: 10.1073/pnas.74.8.3391.
本文引用的文献
1
Virus interference. II. Some properties of interferon.病毒干扰。二、干扰素的一些特性。
Proc R Soc Lond B Biol Sci. 1957 Sep 12;147(927):268-73. doi: 10.1098/rspb.1957.0049.
2
Virus interference. I. The interferon.病毒干扰。一、干扰素。
Proc R Soc Lond B Biol Sci. 1957 Sep 12;147(927):258-67. doi: 10.1098/rspb.1957.0048.
3
Inhibitors of ribosome functions.核糖体功能抑制剂。
Annu Rev Microbiol. 1971;25:487-562. doi: 10.1146/annurev.mi.25.100171.002415.
4
Interferon induction and action.干扰素的诱导与作用。
Annu Rev Microbiol. 1971;25:333-60. doi: 10.1146/annurev.mi.25.100171.002001.
5
Current concepts of interferon and interferon induction.干扰素与干扰素诱导的当前概念
Annu Rev Med. 1970;21:17-46. doi: 10.1146/annurev.me.21.020170.000313.
6
Production of high-titered interferon in cultures of human diploid cells.在人二倍体细胞培养物中产生高滴度干扰素。
Antimicrob Agents Chemother. 1972 Dec;2(6):476-84. doi: 10.1128/AAC.2.6.476.
7
Interferon messenger RNA: translation in heterologous cells.干扰素信使核糖核酸：在异源细胞中的翻译
Proc Natl Acad Sci U S A. 1972 May;69(5):1203-7. doi: 10.1073/pnas.69.5.1203.
8
Stabilization of interferon messenger RNA activity by treatment of cells with metabolic inhibitors and lowering of the incubation temperature.通过用代谢抑制剂处理细胞并降低孵育温度来稳定干扰素信使核糖核酸的活性。
Proc Natl Acad Sci U S A. 1973 Dec;70(12):3909-13. doi: 10.1073/pnas.70.12.3909.
9
The induction of interferon and its messenger RNA in human fibroblasts.人成纤维细胞中干扰素及其信使核糖核酸的诱导
Biochem Biophys Res Commun. 1974 Aug 5;59(3):1023-30. doi: 10.1016/s0006-291x(74)80082-3.
10
Two forms of mouse interferon messenger RNA.小鼠干扰素信使核糖核酸的两种形式。
Biochem Biophys Res Commun. 1974 Aug 5;59(3):1031-8. doi: 10.1016/s0006-291x(74)80083-5.
Zotero 插件