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Dolastatin 3 and two novel cyclic peptides from a palauan collection of Lyngbya majuscula.

作者信息

Mitchell S S, Faulkner D J, Rubins K, Bushman F D

机构信息

Scripps Institution of Oceanography, University of California at San Diego, La Jolla, California 92093-0212, USA.

出版信息

J Nat Prod. 2000 Feb;63(2):279-82. doi: 10.1021/np990353f.

Abstract

A collection of Lyngbya majuscula from Palau contained the peptides dolastatin 3 (1), homodolastatin 3 (2), and kororamide (3), together with aplysiatoxin (4), debromoaplysiatoxin (5), and oscillatoxin A (6). The structures of the new peptides homodolastatin 3 (2) and kororamide (3) were determined by interpretation of spectroscopic data and chemical degradation.

摘要

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