Phillips B, Young T, Finn L, Asher K, Hening W A, Purvis C
Department of Medicine, University of Kentucky College of Medicine, Lexington, USA.
Arch Intern Med. 2000 Jul 24;160(14):2137-41. doi: 10.1001/archinte.160.14.2137.
Restless legs syndrome (RLS) is a disorder characterized by sleep-disrupting unpleasant leg sensations, often accompanied by daytime behavioral problems. Treatment for this condition is available, but it is suspected that most instances of RLS remain undiagnosed. The goal of this investigation was to assess the prevalence and health status correlates of restless legs symptoms (hereinafter referred to as restless legs) in the general population.
A question reflecting the clinical features of RLS was added to the 1996 Kentucky Behavioral Risk Factor Surveillance Survey. Data on the frequency of experiencing restless legs, self-rated general and mental health status, demographics, and behavioral risk factors were collected by telephone interview from 1803 men and women, 18 years and older.
Experiencing restless legs 5 or more nights per month was reported by 3% of participants aged 18 to 29 years, 10% of those aged 30 to 79 years, and 19% of those 80 years and older. The age-adjusted prevalence for Kentucky adults is 10.0%; prevalence did not vary significantly by sex. The adjusted odds ratios (95% confidence intervals) for restless legs and diminished general health and poor mental health status were 2.4 (1.4-4.0) and 3.1 (2.0-4.6), respectively. Restless legs were significantly associated with increased age and body mass index, lower income, smoking, lack of exercise, low alcohol consumption, and diabetes.
The prevalence of restless legs in the general adult population is high. Restless legs may be associated with decreased well-being, emphasizing the need for further research and greater medical recognition of this condition.
不宁腿综合征（RLS）是一种以扰乱睡眠的腿部不适感为特征的病症，常伴有日间行为问题。针对这种病症有相应的治疗方法，但据推测，大多数RLS病例仍未得到诊断。本调查的目的是评估普通人群中不宁腿症状（以下简称不宁腿）的患病率及其与健康状况的相关性。
在1996年肯塔基州行为危险因素监测调查中增加了一个反映RLS临床特征的问题。通过电话访谈收集了1803名18岁及以上男女关于经历不宁腿的频率、自我评定的总体和心理健康状况、人口统计学特征以及行为危险因素的数据。
18至29岁的参与者中有3%报告每月有5个或更多夜晚出现不宁腿，30至79岁的参与者中有10%，80岁及以上的参与者中有19%。肯塔基州成年人经年龄调整后的患病率为10.0%；患病率在性别上无显著差异。不宁腿与总体健康状况下降和心理健康状况不佳的调整后比值比（95%置信区间）分别为2.4（1.4 - 4.0）和3.1（2.0 - 4.6）。不宁腿与年龄增加、体重指数升高、收入较低、吸烟、缺乏运动、低酒精摄入量以及糖尿病显著相关。
普通成年人群中不宁腿的患病率较高。不宁腿可能与幸福感降低有关，这强调了对该病症进行进一步研究并提高医学认知的必要性。
