梅毒螺旋体（Nichols株）在体外运动性和毒力的保持
Retention of motility and virulence of Treponema pallidum (Nichols strain) in vitro.
作者信息
Graves S R, Sandok P L, Jenkin H M, Johnson R C
出版信息
Infect Immun. 1975 Nov;12(5):1116-20. doi: 10.1128/iai.12.5.1116-1120.1975.
Abstract
A maintenance medium for Treponema pallidum was designed to hold its Eh at the optimum for that organism, -10 to -110 mV. After 100% motile (freshly harvested) T. pallidum was inoculated into the medium, the motility of the treponemes decreased to 80% after 2 days, 50% after 3.5 days, and 0% after 9 days during incubation at 34 C. Full virulence was retained for 2 days, but it dropped rapidly thereafter, and the treponemes became avirulent by day 5.
摘要
一种用于梅毒螺旋体的维持培养基被设计用于将其氧化还原电位保持在该生物体的最佳水平，即-10至-110毫伏。将100%活动（刚收获）的梅毒螺旋体接种到培养基中后，在34℃培养期间，螺旋体的活动力在2天后降至80%，3.5天后降至50%，9天后降至0%。其完全毒力保持2天，但此后迅速下降，到第5天螺旋体变得无毒力。
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本文引用的文献
1
2
The isolation from beef serum of a survival factor for Treponema pallidum.从牛肉血清中分离出梅毒螺旋体的一种生存因子。
J Biol Chem. 1951 Jul;191(1):35-41.
3
Factors influencing the in vitro survival of Treponema pallidum.影响梅毒螺旋体体外存活的因素。
Am J Hyg. 1960 May;71:401-17. doi: 10.1093/oxfordjournals.aje.a120123.
4
Ionic requirements of Treponema pallidum. I. Sodium and potassium.梅毒螺旋体的离子需求。I. 钠和钾。
J Bacteriol. 1959 Mar;77(3):322-7. doi: 10.1128/jb.77.3.322-327.1959.
5
Studies of the Treponema pallidum immobilization (TPI) test. IV. A simplified method of preparing the modified basal medium.梅毒螺旋体制动（TPI）试验的研究。IV. 制备改良基础培养基的简化方法。
Am J Syph Gonorrhea Vener Dis. 1954 Jul;38(4):288-94.
6
A modification of the Nelson treponemal sustaining medium for use in the Treponema pallidum immobilization test.一种用于梅毒螺旋体固定试验的改良纳尔逊梅毒螺旋体维持培养基。
Am J Syph Gonorrhea Vener Dis. 1953 Mar;37(2):112-27.
7
Studies of the Treponema pallidum immobilization test. I. The effect of increased sodium thioglycollate and complement.梅毒螺旋体固定试验的研究。I. 硫代乙醇酸钠和补体增加的影响。
Am J Syph Gonorrhea Vener Dis. 1953 Mar;37(2):101-5.
8
Study of the effect of pH and Eh values of the Nelson-Diesendruck medium on the survival of virulent Treponema pallidum.尼尔森-迪森德鲁克培养基的pH值和氧化还原电位对毒力梅毒螺旋体存活影响的研究
Arch Immunol Ther Exp (Warsz). 1966;14(4):445-53.
9
Response of Treponema pallidum to certain nutrilites.梅毒螺旋体对某些营养素的反应。
Br J Vener Dis. 1968 Dec;44(4):274-6. doi: 10.1136/sti.44.4.274.
10
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Infect Immun. 1974 Dec;10(6):1350-5. doi: 10.1128/iai.10.6.1350-1355.1974.
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