Shah S, Peat J K, Mazurski E J, Wang H, Sindhusake D, Bruce C, Henry R L, Gibson P G
Primary Health Care Education and Research Unit, Auburn Hospital and Community Health Services, Auburn, NSW 2144, Australia.
BMJ. 2001 Mar 10;322(7286):583-5. doi: 10.1136/bmj.322.7286.583.
To determine the effect of a peer led programme for asthma education on quality of life and related morbidity in adolescents with asthma.
Cluster randomised controlled trial.
Six high schools in rural Australia.
272 students with recent wheeze, recruited from a cohort of 1515 students from two school years (mean age 12.5 and 15.5 years); 251 (92.3%) completed the study.
A structured education programme for peers comprising three steps (the "Triple A Program").
Quality of life, school absenteeism, asthma attacks, and lung function.
When adjusted for year and sex, mean total quality of life scores showed significant improvement in the intervention than control group. Clinically important improvement in quality of life (>0.5 units) occurred in 25% of students with asthma in the intervention group compared with 12% in the control group (P=0.01). The number needed to treat was 8 (95% confidence interval 4.5 to 35.7). The effect of the intervention was greatest in students in year 10 and in females. Significant improvements occurred in the activities domain (41% v 28%) and in the emotions domain (39% v 19%) in males in the intervention group. School absenteeism significantly decreased in the intervention group only. Asthma attacks at school increased in the control group only.
The triple A programme leads to a clinically relevant improvement in quality of life and related morbidity in students with asthma. Wider dissemination of this programme in schools could play an important part in reducing the burden of asthma in adolescents.
确定同伴主导的哮喘教育项目对青少年哮喘患者生活质量及相关发病率的影响。
整群随机对照试验。
澳大利亚农村的六所高中。
从两个学年的1515名学生队列中招募的272名近期有喘息症状的学生(平均年龄12.5岁和15.5岁);251名(92.3%)完成了研究。
针对同伴的结构化教育项目,包括三个步骤(“AAA项目”)。
生活质量、学校缺勤率、哮喘发作及肺功能。
在对年级和性别进行调整后,干预组的平均生活质量总分较对照组有显著改善。干预组25%的哮喘学生生活质量有临床意义的改善(>0.5分),而对照组为12%(P=0.01)。治疗所需人数为8(95%置信区间4.5至35.7)。干预措施对10年级学生和女性的效果最为显著。干预组男性在活动领域(41%对28%)和情绪领域(39%对19%)有显著改善。仅干预组的学校缺勤率显著降低。仅对照组的学校哮喘发作次数增加。
AAA项目可使哮喘学生的生活质量及相关发病率在临床上得到有意义的改善。在学校更广泛地推广该项目可能对减轻青少年哮喘负担起到重要作用。