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马初乳中一种异常磷酸化的N-乙酰乳糖胺的出现。

Occurrence of an unusual phosphorylated N-acetyllactosamine in horse colostrum.

作者信息

Nakamura T, Amikawa S, Harada T, Saito T, Arai I, Urashima T

机构信息

Department of Bioresource, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan.

出版信息

Biochim Biophys Acta. 2001 Feb 16;1525(1-2):13-8. doi: 10.1016/s0304-4165(00)00148-3.

Abstract

The colostrum of horses (thoroughbreds) was extracted and fractionated to yield Gal(beta1-4)GlcNAcalpha1-phosphate, which has not previously been detected in any mammalian milk or colostrum, as well as Neu5Ac(alpha2-3)Gal(beta1-4)Glc. The structures of these saccharides were established by NMR spectroscopy and MALDI-TOF mass spectrometry.

摘要

提取并分离了马(纯种马)的初乳,得到了Gal(β1-4)GlcNAcα1-磷酸,此前在任何哺乳动物的乳汁或初乳中均未检测到该物质,同时还得到了Neu5Ac(α2-3)Gal(β1-4)Glc。这些糖类的结构通过核磁共振光谱和基质辅助激光解吸电离飞行时间质谱得以确定。

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