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用于调强放射治疗的一种商用多叶准直器的特性描述。

Characterization of a commercial multileaf collimator used for intensity modulated radiation therapy.

作者信息

Low D A, Sohn J W, Klein E E, Markman J, Mutic S, Dempsey J F

机构信息

Radiation Oncology Center, Mallinckrodt Institute of Radiology, St. Louis, Missouri 63110, USA.

出版信息

Med Phys. 2001 May;28(5):752-6. doi: 10.1118/1.1367863.

Abstract

The characteristics of a commercial multileaf collimator (MLC) to deliver static and dynamic multileaf collimation (SMLC and DMLC, respectively) were investigated to determine their influence on intensity modulated radiation therapy (IMRT) treatment planning and quality assurance. The influence of MLC leaf positioning accuracy on sequentially abutted SMLC fields was measured by creating abutting fields with selected gaps and overlaps. These data were also used to measure static leaf positioning precision. The characteristics of high leaf-velocity DMLC delivery were measured with constant velocity leaf sequences starting with an open field and closing a single leaf bank. A range of 1-72 monitor units (MU) was used providing a range of leaf velocities. The field abutment measurements yielded dose errors (as a percentage of the open field max dose) of 16.7+/-0.7% mm(-1) and 12.8+/-0.7% mm(-1) for 6 MV and 18 MV photon beams, respectively. The MLC leaf positioning precision was 0.080+/-0.018 mm (single standard deviation) highlighting the excellent delivery hardware tolerances for the tested beam delivery geometry. The high leaf-velocity DMLC measurements showed delivery artifacts when the leaf sequence and selected monitor units caused the linear accelerator to move the leaves at their maximum velocity while modulating the accelerator dose rate to deliver the desired leaf and MU sequence (termed leaf-velocity limited delivery). According to the vendor, a unique feature to their linear accelerator and MLC is that the dose rate is reduced to provide the correct cm MU(-1) leaf velocity when the delivery is leaf-velocity limited. However, it was found that the system delivered roughly 1 MU per pulse when the delivery was leaf-velocity limited causing dose profiles to exhibit discrete steps rather than a smooth dose gradient. The root mean square difference between the steps and desired linear gradient was less than 3% when more than 4 MU were used. The average dose per MU was greater and less than desired for closing and opening leaf patterns, respectively, when the delivery was leaf-velocity limited. The results indicated that the dose delivery artifacts should be minor for most clinical cases, but limit the assumption of dose linearity when significantly reducing the delivered dose for dosimeter characterization studies or QA measurements.

摘要

研究了一种商用多叶准直器(MLC)用于实现静态和动态多叶准直(分别为SMLC和DMLC)的特性,以确定它们对调强放射治疗(IMRT)治疗计划和质量保证的影响。通过创建具有选定间隙和重叠的相邻野,测量了MLC叶片定位精度对顺序相邻SMLC野的影响。这些数据也用于测量静态叶片定位精度。使用从开放野开始并关闭单个叶片组的等速叶片序列测量了高叶片速度DMLC输送的特性。使用了1 - 72个监测单位(MU)的范围,提供了一系列叶片速度。野相邻测量得出,对于6 MV和18 MV光子束,剂量误差(作为开放野最大剂量的百分比)分别为16.7±0.7% mm⁻¹和12.8±0.7% mm⁻¹。MLC叶片定位精度为0.080±0.018 mm(单标准偏差),突出了针对测试的射束输送几何结构的出色输送硬件容差。高叶片速度DMLC测量显示,当叶片序列和选定的监测单位导致直线加速器以其最大速度移动叶片,同时调制加速器剂量率以输送所需的叶片和MU序列时(称为叶片速度受限输送),会出现输送伪影。根据供应商的说法,其直线加速器和MLC的一个独特特性是,当输送为叶片速度受限时,剂量率会降低以提供正确的每厘米MU的叶片速度。然而,发现当输送为叶片速度受限时,系统每个脉冲大致输送1 MU,导致剂量分布呈现离散的台阶而不是平滑的剂量梯度。当使用超过4 MU时,台阶与所需线性梯度之间的均方根差值小于3%。当输送为叶片速度受限时,对于关闭和打开叶片模式,每个MU的平均剂量分别大于和小于预期。结果表明,对于大多数临床病例,剂量输送伪影应较小,但在为剂量计特性研究或质量保证测量显著降低输送剂量时,会限制剂量线性的假设。

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