一种用于诊断人类钩端螺旋体病的间接血凝试验的评估
Evaluation of an indirect hemagglutination test for the diagnosis of human leptospirosis.
作者信息
Sulzer C R, Glosser J W, Rogers F, Jones W L, Frix M
出版信息
J Clin Microbiol. 1975 Sep;2(3):218-21. doi: 10.1128/jcm.2.3.218-221.1975.
Abstract
A presumptive hemagglutination test for the serological diagnosis of leptospirosis in humans is described. The antigen was prepared from a soluble alcohol extract of an andamana strain sorbed to human O-negative erythrocytes and preserved by pyruvic aldehyde fixation. In this study, the overall sensitivity of the hemagglutination test was 92% in contrast to 69% for the presumptive slide agglutination test. The specificity was 95% for the hemagglutination test in comparison with 83% for the slide test.
摘要
本文描述了一种用于人类钩端螺旋体病血清学诊断的推定血凝试验。抗原由吸附于人类O型阴性红细胞上的安达马纳菌株的可溶性乙醇提取物制备，并通过丙酮酸醛固定保存。在本研究中，血凝试验的总体敏感性为92%，而推定玻片凝集试验为69%。血凝试验的特异性为95%，而玻片试验为83%。
相似文献
1
Evaluation of an indirect hemagglutination test for the diagnosis of human leptospirosis.一种用于诊断人类钩端螺旋体病的间接血凝试验的评估
J Clin Microbiol. 1975 Sep;2(3):218-21. doi: 10.1128/jcm.2.3.218-221.1975.
2
Indirect hemagglutination test for detection of leptospiral antibodies.用于检测钩端螺旋体抗体的间接血凝试验。
Jpn J Exp Med. 1974 Apr;44(2):191-7.
3
[A comparative evaluation of the sensitivity of different methods for the serological diagnosis of leptospirosis].[不同方法用于钩端螺旋体病血清学诊断的敏感性比较评估]
Zh Mikrobiol Epidemiol Immunobiol. 1990 Dec(12):73-7.
4
[Prospects of using the immunoadhesive hemagglutination reaction for leptospirosis diagnosis].[免疫粘附血凝反应用于钩端螺旋体病诊断的前景]
Tr Inst Im Pastera. 1983;60:119-23.
5
Quantitative assay for genus-specific leptospiral antigen and antibody.钩端螺旋体属特异性抗原和抗体的定量测定。
Appl Microbiol. 1973 Apr;25(4):697-8. doi: 10.1128/am.25.4.697-698.1973.
6
Development of a simple serological method for diagnosing leptospirosis: a microcapsule agglutination test.一种用于诊断钩端螺旋体病的简单血清学方法的开发：微胶囊凝集试验。
J Clin Microbiol. 1982 May;15(5):835-41. doi: 10.1128/jcm.15.5.835-841.1982.
7
[The development and evaluation of a leptospiral polyvalent antigenic erythrocytic diagnostic agent].[钩端螺旋体多价抗原红细胞诊断制剂的研制与评价]
Zh Mikrobiol Epidemiol Immunobiol. 1995 Nov-Dec(6):79-80.
8
Comparison of a slide agglutination test, LeptoTek Dri-Dot, and IgM-ELISA with microscopic agglutination test for Leptospira antibody detection.玻片凝集试验、LeptoTek Dri-Dot和IgM-ELISA与显微镜凝集试验检测钩端螺旋体抗体的比较。
Southeast Asian J Trop Med Public Health. 2007 Nov;38(6):1111-4.
9
Serologic diagnosis of leptospirosis: comparison of line blot and immunofluorescence techniques with the genus-specific microscopic agglutination test.钩端螺旋体病的血清学诊断：线印迹法和免疫荧光技术与属特异性显微镜凝集试验的比较
J Infect Dis. 1989 Oct;160(4):734-5. doi: 10.1093/infdis/160.4.734.
10
Genus-specific leptospiral antigen and its possible use in laboratory diagnosis.属特异性钩端螺旋体抗原及其在实验室诊断中的可能应用。
J Clin Pathol. 1973 Jan;26(1):7-16. doi: 10.1136/jcp.26.1.7.
引用本文的文献
1
Leptospirosis: an occupational hazard to veterinarians.钩端螺旋体病：兽医的职业危害。
Can Vet J. 1986 Feb;27(2):78-81.
2
Evaluation of four commercially available rapid serologic tests for diagnosis of leptospirosis.评估四种市售快速血清学检测方法用于诊断钩端螺旋体病的效果。
J Clin Microbiol. 2003 Feb;41(2):803-9. doi: 10.1128/JCM.41.2.803-809.2003.
3
Evaluation of eight rapid screening tests for acute leptospirosis in Hawaii.夏威夷急性钩端螺旋体病八种快速筛查检测方法的评估
J Clin Microbiol. 2002 Apr;40(4):1464-9. doi: 10.1128/JCM.40.4.1464-1469.2002.
4
Diagnosis of human leptospirosis by monoclonal antibody-based antigen detection in urine.基于单克隆抗体的尿液抗原检测法诊断人类钩端螺旋体病
J Clin Microbiol. 2002 Feb;40(2):480-9. doi: 10.1128/JCM.40.3.480-489.2002.
5
Leptospirosis.钩端螺旋体病
Clin Microbiol Rev. 2001 Apr;14(2):296-326. doi: 10.1128/CMR.14.2.296-326.2001.
6
An evaluation of three commercial kits for use as screening methods for the detection of leptospiral antibodies in the UK.对英国三种用于检测钩端螺旋体抗体筛查方法的商用试剂盒的评估。
J Clin Pathol. 2001 Jan;54(1):25-30. doi: 10.1136/jcp.54.1.25.
7
Lateral-flow assay for rapid serodiagnosis of human leptospirosis.用于人类钩端螺旋体病快速血清学诊断的侧向流动分析法。
Clin Diagn Lab Immunol. 2001 Jan;8(1):166-9. doi: 10.1128/CDLI.8.1.166-169.2001.
8
Evaluation of the indirect hemagglutination assay for diagnosis of acute leptospirosis in Hawaii.夏威夷地区间接血凝试验用于诊断急性钩端螺旋体病的评估
J Clin Microbiol. 2000 Mar;38(3):1081-4. doi: 10.1128/JCM.38.3.1081-1084.2000.
9
Evaluation of the indirect hemagglutination assay for diagnosis of acute leptospirosis.间接血凝试验用于诊断急性钩端螺旋体病的评估。
J Clin Microbiol. 1998 Jan;36(1):11-4. doi: 10.1128/JCM.36.1.11-14.1998.
10
Evaluation of a passive microcapsule agglutination test for the screening of human leptospirosis.用于人类钩端螺旋体病筛查的被动微胶囊凝集试验的评估
Eur J Epidemiol. 1993 Jan;9(1):92-6. doi: 10.1007/BF00463096.
本文引用的文献
1
Serological studies on hemolytic antigen from Leptospira.关于钩端螺旋体溶血抗原的血清学研究。
Proc Soc Exp Biol Med. 1958 Jun;98(2):265-9. doi: 10.3181/00379727-98-24012.
2
Evaluation of the hemolytic test in the serodiagnosis of human leptospirosis.人钩端螺旋体病血清学诊断中溶血试验的评估
J Infect Dis. 1957 Sep-Oct;101(2):210-8. doi: 10.1093/infdis/101.2.210.
3
Standardization and stabilization of an extract from Leptospira biflexa and its use in the hemolytic test for leptospirosis.双曲钩端螺旋体提取物的标准化与稳定化及其在钩端螺旋体病溶血试验中的应用。
J Infect Dis. 1957 Sep-Oct;101(2):203-9. doi: 10.1093/infdis/101.2.203.
4
Evaluation of a hemagglutination test for human leptospirosis.人钩端螺旋体病血凝试验的评估
Appl Microbiol. 1973 Nov;26(5):655-7. doi: 10.1128/am.26.5.655-657.1973.
5
Improved microtechnique for the leptospiral microscopic agglutination test.用于钩端螺旋体显微镜凝集试验的改良显微技术。
Appl Microbiol. 1973 Jun;25(6):976-80. doi: 10.1128/am.25.6.976-980.1973.
6
Quantitative assay for genus-specific leptospiral antigen and antibody.钩端螺旋体属特异性抗原和抗体的定量测定。
Appl Microbiol. 1973 Apr;25(4):697-8. doi: 10.1128/am.25.4.697-698.1973.
7
Studies on indirect hemagglutination test for leptospirosis.
Jpn J Exp Med. 1972 Dec;42(6):563-8.
Zotero 插件