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本文引用的文献

1
A trial of a test-and-treat strategy for Helicobacter pylori positive dyspeptic patients in general practice.一项针对全科医疗中幽门螺杆菌阳性消化不良患者的检测与治疗策略试验。
Int J Clin Pract. 1999 Sep;53(6):413-6.
2
Low-dose lansoprazole provides greater relief of heartburn and epigastric pain than low-dose omeprazole in patients with acid-related dyspepsia.在患有酸相关性消化不良的患者中，低剂量兰索拉唑比低剂量奥美拉唑能更有效地缓解烧心和上腹部疼痛。
Aliment Pharmacol Ther. 1999 Mar;13(3):413-9. doi: 10.1046/j.1365-2036.1999.00455.x.
3
First line treatment with omeprazole provides an effective and superior alternative strategy in the management of dyspepsia compared to antacid/alginate liquid: a multicentre study in general practice.与抗酸剂/藻酸盐液体相比，奥美拉唑一线治疗在消化不良管理中提供了一种有效且更优的替代策略：一项全科医学多中心研究。
Aliment Pharmacol Ther. 1998 Feb;12(2):147-57. doi: 10.1046/j.1365-2036.1998.0284f.x.
4
The management of acid-related dyspepsia in general practice: a comparison of an omeprazole versus an antacid-alginate/ranitidine management strategy. Compete Research Group [corrected].全科医疗中酸相关性消化不良的管理：奥美拉唑与抗酸剂-藻酸盐/雷尼替丁管理策略的比较。竞争研究小组[已校正]
Aliment Pharmacol Ther. 1998 Mar;12(3):263-71. doi: 10.1046/j.1365-2036.1998.00282.x.
5
Lansoprazole 30 mg daily versus ranitidine 150 mg b.d. in the treatment of acid-related dyspepsia in general practice.在全科医疗中，兰索拉唑每日30毫克与雷尼替丁每日两次、每次150毫克治疗酸相关性消化不良的比较。
Aliment Pharmacol Ther. 1997 Jun;11(3):541-6. doi: 10.1046/j.1365-2036.1997.00179.x.
6
Empirical H2-blocker therapy or prompt endoscopy in management of dyspepsia.经验性使用H2受体阻滞剂治疗或及时进行内镜检查以管理消化不良。
Lancet. 1994 Apr 2;343(8901):811-6. doi: 10.1016/s0140-6736(94)92023-0.
7
Prospective screening of dyspeptic patients by Helicobacter pylori serology.通过幽门螺杆菌血清学对消化不良患者进行前瞻性筛查。
Lancet. 1995 Nov 18;346(8986):1315-8. doi: 10.1016/s0140-6736(95)92340-3.
8
Self-care and primary care of dyspepsia: a review.
Fam Pract. 1987 Mar;4(1):68-77. doi: 10.1093/fampra/4.1.68.
9
Factors affecting the decision to consult with dyspepsia: comparison of consulters and non-consulters.影响消化不良患者就诊决策的因素：就诊者与未就诊者的比较
J R Coll Gen Pract. 1989 Dec;39(329):495-8.
10
Dyspepsia in England and Scotland.英格兰和苏格兰的消化不良
Gut. 1990 Apr;31(4):401-5. doi: 10.1136/gut.31.4.401.

未查明原因的消化不良的处理方法。

Approaches to uninvestigated dyspepsia.

作者信息

Jones R H

机构信息

Department of General Practice and Primary Care, Guy's, King's and St Thomas' School of Medicine, 5 Lambeth Walk, London, SE11 6SP, UK.

出版信息

Gut. 2002 May;50 Suppl 4(Suppl 4):iv42-6. doi: 10.1136/gut.50.suppl_4.iv42.

DOI:10.1136/gut.50.suppl_4.iv42
PMID:11953347
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1867704/
Abstract

Uninvestigated dyspepsia refers to patients with new or recurrent dyspeptic symptoms in whom no investigations have previously been undertaken. These patients are much more likely to present in primary than in secondary care. It is particularly important to be able to offer effective symptom relief to support the explanation, reassurance, and advice provided to patients, and low dose or standard dose proton pump inhibitor therapy appears to offer the most effective approach to empirical therapy of this kind.

摘要

未经检查的消化不良是指有新出现或复发性消化不良症状、之前未进行过任何检查的患者。这些患者在初级医疗保健机构就诊的可能性远高于二级医疗保健机构。能够提供有效的症状缓解措施以支持向患者提供的解释、安抚和建议尤为重要，低剂量或标准剂量质子泵抑制剂治疗似乎为此类经验性治疗提供了最有效的方法。