Fabbri A, Marchesini G, Morselli-Labate A M, Rossi F, Cicognani A, Dente M, Iervese T, Ruggeri S, Mengozzi U, Vandelli A
Dipartimento Emergenza-Urgenza Accettazione, Ospedale GB Morgagni, Azienda Unità Sanitaria Locale di Forlì, Italy.
Emerg Med J. 2002 May;19(3):210-4. doi: 10.1136/emj.19.3.210.
To examine if a positive blood alcohol concentration (BAC) at the time of crash (>or=0.50 g/l), independently of any clinical evidence and laboratory results indicating acute alcohol intoxication, is associated with specific features of patients involved, specific types of injury, and characteristics of the accident.
In this prospective cohort study, the BAC was measured in adult patients who had been injured and who were admitted to an Italian emergency department within four hours after a road accident. Altogether 2354 trauma patients were included between January to December 1998 out of 2856 eligible subjects.
BAC exceeded 0.50 g/l in 425 subjects (18.1%), but was in a toxic range (>1.00 g/l) in only 179 subjects (7.6%). BAC positivity was significantly more common in men, in young subjects, in subjects driving cars or trucks, and in persons involved in a crash during night time and at weekends. It was associated with higher trauma severity, but no differences were found in injury body distribution according to vehicle type. In multivariate logistic regression analysis, the risk of a positive BAC in injured patients at the time of crash was independently associated with night time (odds ratio: 3.48; 95% confidence intervals: 2.46 to 4.91), male sex (3.08 (2.36 to 4.01)), weekend nights (1.21 (1.05 to 1.41)), and age (0.92 (0.86 to 0.99) per decades).
In injured patients after a road accident, a BAC at the time of crash in a non-toxic range (>or=0.50 g/l) is associated with specific characteristics of crash, as well as increased risk of higher trauma severity. More careful monitoring is needed in young men during weekend nights for highest risk of BAC positivity after a road accident.
探讨车祸发生时血液酒精浓度（BAC）呈阳性（≥0.50 g/l），在不考虑任何表明急性酒精中毒的临床证据和实验室结果的情况下，是否与事故中受伤患者的特定特征、特定损伤类型以及事故特征相关。
在这项前瞻性队列研究中，对道路交通事故发生后4小时内受伤并被送往意大利急诊科的成年患者测量BAC。在1998年1月至12月期间，从2856名符合条件的受试者中总共纳入了2354名创伤患者。
425名受试者（18.1%）的BAC超过0.50 g/l，但只有179名受试者（7.6%）处于中毒范围（>1.00 g/l）。BAC呈阳性在男性、年轻受试者、驾驶汽车或卡车的受试者以及夜间和周末发生车祸的人群中显著更为常见。它与更高的创伤严重程度相关，但根据车辆类型，在损伤身体分布方面未发现差异。在多因素逻辑回归分析中，受伤患者车祸发生时BAC呈阳性的风险与夜间（比值比：3.48；95%置信区间：2.46至4.91）、男性（3.08（2.36至4.01））、周末夜间（1.21（1.05至1.41））以及年龄（每十岁0.92（0.86至0.99））独立相关。
在道路交通事故后的受伤患者中，车祸发生时处于无毒范围（≥0.50 g/l）的BAC与车祸的特定特征以及更高创伤严重程度的风险增加相关。在周末夜间，年轻男性需要更仔细的监测，因为他们在道路交通事故后BAC呈阳性的风险最高。
