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本文引用的文献

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Characterisation of rotaviruses from children treated at a London hospital during 1996: emergence of strains G9P2A[6] and G3P2A[6].1996年伦敦一家医院收治儿童的轮状病毒特征分析：G9P2A[6]和G3P2A[6]毒株的出现
J Med Virol. 2000 May;61(1):150-4. doi: 10.1002/(sici)1096-9071(200005)61:1<150::aid-jmv24>3.0.co;2-w.
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New P serotype of group A human rotavirus closely related to that of a porcine rotavirus.与猪轮状病毒密切相关的新型A组人轮状病毒血清型
J Med Virol. 2000 Jan;60(1):63-9.
3
Evidence of high-frequency genomic reassortment of group A rotavirus strains in Bangladesh: emergence of type G9 in 1995.孟加拉国A组轮状病毒株高频基因组重配的证据：1995年G9型的出现。
J Clin Microbiol. 1999 Jun;37(6):1885-91. doi: 10.1128/JCM.37.6.1885-1891.1999.
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Viral diarrhea in children in Beijing, China.中国北京儿童的病毒性腹泻
J Med Virol. 1999 Apr;57(4):390-6.
5
Rotavirus G and P types in children with acute diarrhea in Blantyre, Malawi, from 1997 to 1998: predominance of novel P[6]G8 strains.1997年至1998年马拉维布兰太尔急性腹泻儿童中的轮状病毒G型和P型：新型P[6]G8毒株占主导地位
J Med Virol. 1999 Mar;57(3):308-12.
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Serological and genomic characterization of human rotaviruses detected in China.在中国检测到的人类轮状病毒的血清学和基因组特征
J Med Virol. 1998 Jun;55(2):168-76. doi: 10.1002/(sici)1096-9071(199806)55:2<168::aid-jmv14>3.0.co;2-e.
7
Rotavirus G and P types circulating in Brazil: characterization by RT-PCR, probe hybridization, and sequence analysis.巴西流行的轮状病毒G型和P型：通过逆转录聚合酶链反应、探针杂交和序列分析进行特征鉴定
Arch Virol. 1996;141(12):2365-74. doi: 10.1007/BF01718637.
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Further characterization of field strains of rotavirus from Nigeria VP4 genotype P6 most frequently identified among symptomatically infected children.
J Trop Pediatr. 1997 Oct;43(5):267-74. doi: 10.1093/tropej/43.5.267.
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Unusual diversity of human rotavirus G and P genotypes in India.印度人类轮状病毒G和P基因型的异常多样性。
J Clin Microbiol. 1996 Feb;34(2):436-9. doi: 10.1128/jcm.34.2.436-439.1996.
10
Review of G and P typing results from a global collection of rotavirus strains: implications for vaccine development.来自全球轮状病毒毒株集合的G和P分型结果综述：对疫苗开发的启示
J Infect Dis. 1996 Sep;174 Suppl 1:S30-6. doi: 10.1093/infdis/174.supplement_1.s30.

中国急性腹泻儿童中轮状病毒株的多样性：1998 - 2000年监测研究

Diversity of rotavirus strains among children with acute diarrhea in China: 1998-2000 surveillance study.

作者信息

Fang Zhao-Yin, Yang Hui, Qi Jin, Zhang Jing, Sun Li-Wei, Tang Jing-Yu, Ma Li, Du Zeng-Qing, He Ai-Hua, Xie Jian-Ping, Lu Yi-Yu, Ji Zhen-Zhou, Zhu Bao-Quan, Wu Hai-Yan, Lin Si-En, Xie Hua-Ping, Griffin Dixie D, Ivanoff Bernard, Glass Roger I, Gentsch Jon R

机构信息

Division of Enteric Viruses, Institute of Virology, Chinese Academy of Preventive Medicine, 100 Ying Xin Jie, Xuan Wu Qu, Beijing 100052, People's Republic of China.

出版信息

J Clin Microbiol. 2002 May;40(5):1875-8. doi: 10.1128/JCM.40.5.1875-1878.2002.

DOI:10.1128/JCM.40.5.1875-1878.2002
PMID:11980983
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC130922/
Abstract

As part of a national rotavirus surveillance activity, we collected fecal specimens from 3,177 children with acute diarrhea in 10 regions of China between April 1998 and April 2000 and screened them for rotavirus. Rotavirus was detected in 41% (n = 1,305) of specimens, and in these, G1 was the predominant serotype (72.6%), followed by G3 (14.2%), G2 (12.1%), G4 (2.5%), G9 (0.9%), and G untypeable (0.7%). Among 327 G-typed strains tested for P genotype, 14 different P-G combinations were identified, with the globally common strains P[8]G1, P[4]G2, P[8]G3, and P[8]G4 representing 75.6% of all typed rotavirus strains. Among the uncommon strains, 11 were P[6]G9, and others included P[6]G1, P[6]G3, and five novel P-G combinations (P[9]G1, P[4]G1, P[4]G3, P[4]G4, and P[8]G2). Our results indicate that while the common rotavirus strains remain predominant, the diversity of strains is much greater than was previously recognized.

摘要

作为一项全国轮状病毒监测活动的一部分，我们于1998年4月至2000年4月期间，在中国10个地区收集了3177名急性腹泻儿童的粪便标本，并对其进行轮状病毒筛查。41%（n = 1305）的标本中检测到轮状病毒，其中G1是主要血清型（72.6%），其次是G3（14.2%）、G2（12.1%）、G4（2.5%）、G9（0.9%）和无法分型的G型（0.7%）。在327株检测P基因型的G型毒株中，鉴定出14种不同的P-G组合，全球常见毒株P[8]G1、P[4]G2、P[8]G3和P[8]G4占所有分型轮状病毒毒株的75.6%。在不常见毒株中，11株为P[6]G9，其他包括P[6]G1、P[6]G3以及5种新的P-G组合（P[9]G1、P[4]G1、P[4]G3、P[4]G4和P[8]G2）。我们的结果表明，虽然常见轮状病毒毒株仍然占主导地位，但毒株的多样性比之前认识到的要大得多。