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(165, 182, 189-S-氨甲酰甲基半胱氨酸)-人生长激素-(140-191)的合成与生物活性

The synthesis and biological activity of (165, 182, 189-S-carbamidomethylcysteine)-human growth hormone-(140-191).

作者信息

Blake J, Li C H

出版信息

Int J Pept Protein Res. 1975;7(6):495-501. doi: 10.1111/j.1399-3011.1975.tb02471.x.

Abstract

The peptide [165, 182, 189-S-carbamidomethylcysteine]-human growth hormone-(140-191) has been synthesized by the solid-phase method. The complement fixation, lactogenic and growth-promoting activities of the synthetic peptide were comparable to that of [165, 182, 189-S-carbamidomethylcysteine]-human growth hormone-(141-191) that was derived from the native hormone.

摘要

肽[165, 182, 189 - S - 氨甲酰甲基半胱氨酸]-人生长激素-(140 - 191)已通过固相法合成。该合成肽的补体结合、催乳和促生长活性与源自天然激素的[165, 182, 189 - S - 氨甲酰甲基半胱氨酸]-人生长激素-(141 - 191)相当。

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