噬菌体PM2具有围绕球形蛋白质脂质核心的蛋白质衣壳。
Bacteriophage PM2 has a protein capsid surrounding a spherical proteinaceous lipid core.
作者信息
Kivelä Hanna M, Kalkkinen Nisse, Bamford Dennis H
机构信息
Department of Biosciences, University of Helsinki, Finland.
出版信息
J Virol. 2002 Aug;76(16):8169-78. doi: 10.1128/jvi.76.16.8169-8178.2002.
Abstract
The marine double-stranded DNA (dsDNA) bacteriophage PM2, studied since 1968, is the type organism of the family Corticoviridae, infecting two gram-negative Pseudoalteromonas species. The virion contains a membrane underneath an icosahedral protein capsid composed of two structural proteins. The purified major capsid protein, P2, appears as a trimer, and the receptor binding protein, P1, appears as a monomer. The C-terminal part of P1 is distal and is responsible for receptor binding activity. The rest of the structural proteins are associated with the internal phospholipid membrane enclosing the viral genome. This internal particle is designated the lipid core. The overall structural organization of phage PM2 resembles that of dsDNA bacteriophage PRD1, the type organism of the family TECTIVIRIDAE:
摘要
自1968年起开始研究的海洋双链DNA（dsDNA）噬菌体PM2，是皮层病毒科的模式生物，可感染两种革兰氏阴性假交替单胞菌属物种。病毒粒子在由两种结构蛋白组成的二十面体蛋白质衣壳下方含有一层膜。纯化后的主要衣壳蛋白P2呈三聚体形式，而受体结合蛋白P1呈单体形式。P1的C末端部分位于远端，负责受体结合活性。其余结构蛋白与包裹病毒基因组的内部磷脂膜相关联。这个内部粒子被称为脂质核心。噬菌体PM2的整体结构组织类似于双链DNA噬菌体PRD1，即 tectiviridae 科的模式生物：
相似文献
1
Bacteriophage PM2 has a protein capsid surrounding a spherical proteinaceous lipid core.
J Virol. 2002 Aug;76(16):8169-78. doi: 10.1128/jvi.76.16.8169-8178.2002.
2
ICTV Virus Taxonomy Profile: Corticoviridae.
J Gen Virol. 2017 May;98(5):888-889. doi: 10.1099/jgv.0.000795.
3
Penetration of membrane-containing double-stranded-DNA bacteriophage PM2 into Pseudoalteromonas hosts.
J Bacteriol. 2004 Aug;186(16):5342-54. doi: 10.1128/JB.186.16.5342-5354.2004.
4
Preliminary crystallographic analysis of the major capsid protein P2 of the lipid-containing bacteriophage PM2.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Aug 1;61(Pt 8):762-5. doi: 10.1107/S174430910502141X. Epub 2005 Jul 30.
5
Insights into virus evolution and membrane biogenesis from the structure of the marine lipid-containing bacteriophage PM2.
Mol Cell. 2008 Sep 5;31(5):749-61. doi: 10.1016/j.molcel.2008.06.026.
6
Genome characterization of lipid-containing marine bacteriophage PM2 by transposon insertion mutagenesis.
J Virol. 2006 Sep;80(18):9270-8. doi: 10.1128/JVI.00536-06.
7
The PM2 virion has a novel organization with an internal membrane and pentameric receptor binding spikes.
Nat Struct Mol Biol. 2004 Sep;11(9):850-6. doi: 10.1038/nsmb807. Epub 2004 Aug 1.
8
A novel lysis system in PM2, a lipid-containing marine double-stranded DNA bacteriophage.
Mol Microbiol. 2007 Jun;64(6):1635-48. doi: 10.1111/j.1365-2958.2007.05769.x.
9
The complete genome sequence of PM2, the first lipid-containing bacterial virus To Be isolated.
Virology. 1999 Sep 30;262(2):355-63. doi: 10.1006/viro.1999.9837.
10
Genetics for Pseudoalteromonas provides tools to manipulate marine bacterial virus PM2.
J Bacteriol. 2008 Feb;190(4):1298-307. doi: 10.1128/JB.01639-07. Epub 2007 Dec 14.
引用本文的文献
1
Oral bacteriophages and their potential as adjunctive treatments for periodontitis: a narrative review.
J Oral Microbiol. 2025 Feb 25;17(1):2469890. doi: 10.1080/20002297.2025.2469890. eCollection 2025.
2
Bacteriophage Receptor Recognition and Nucleic Acid Transfer.
Subcell Biochem. 2024;105:593-628. doi: 10.1007/978-3-031-65187-8_17.
3
Integrative Approaches to Study Virus Structures.
Subcell Biochem. 2024;105:247-297. doi: 10.1007/978-3-031-65187-8_7.
4
Jorvik: A membrane-containing phage that will likely found a new family within Vinavirales.
iScience. 2023 Sep 29;26(11):108104. doi: 10.1016/j.isci.2023.108104. eCollection 2023 Nov 17.
5
Bacteriophages in Biological Wastewater Treatment Systems: Occurrence, Characterization, and Function.
Front Microbiol. 2021 Sep 30;12:730071. doi: 10.3389/fmicb.2021.730071. eCollection 2021.
6
Bacteriophage Capsid Modification by Genetic and Chemical Methods.
Bioconjug Chem. 2021 Mar 17;32(3):466-481. doi: 10.1021/acs.bioconjchem.1c00018. Epub 2021 Mar 4.
7
Genome Sequence of PM2-Like Phage Cr39582, Induced from a Pseudoalteromonas sp. Isolated from the Gut of Ciona robusta.
Genome Announc. 2018 May 24;6(21):e00368-18. doi: 10.1128/genomeA.00368-18.
8
ICTV Virus Taxonomy Profile: Corticoviridae.
J Gen Virol. 2017 May;98(5):888-889. doi: 10.1099/jgv.0.000795.
9
Ultrastructure and Viral Metagenome of Bacteriophages from an Anaerobic Methane Oxidizing Bioreactor Enrichment Culture.
Front Microbiol. 2016 Nov 8;7:1740. doi: 10.3389/fmicb.2016.01740. eCollection 2016.
10
Archaeal Haloarcula californiae Icosahedral Virus 1 Highlights Conserved Elements in Icosahedral Membrane-Containing DNA Viruses from Extreme Environments.
mBio. 2016 Jul 19;7(4):e00699-16. doi: 10.1128/mBio.00699-16.
本文引用的文献
1
A rapid method of total lipid extraction and purification.
Can J Biochem Physiol. 1959 Aug;37(8):911-7. doi: 10.1139/o59-099.
2
Assembly of bacteriophage PRD1 spike complex: role of the multidomain protein P5.
Biochemistry. 2000 Aug 29;39(34):10566-73. doi: 10.1021/bi000711+.
3
Purification and protein composition of PM2, the first lipid-containing bacterial virus to be isolated.
Virology. 1999 Sep 30;262(2):364-74. doi: 10.1006/viro.1999.9838.
4
The complete genome sequence of PM2, the first lipid-containing bacterial virus To Be isolated.
Virology. 1999 Sep 30;262(2):355-63. doi: 10.1006/viro.1999.9837.
5
Analysis of the multimeric state of proteins by matrix assisted laser desorption/ionization mass spectrometry after cross-linking with glutaraldehyde.
Rapid Commun Mass Spectrom. 1999;13(3):185-90. doi: 10.1002/(SICI)1097-0231(19990215)13:3<185::AID-RCM481>3.0.CO;2-O.
6
DNA packaging orders the membrane of bacteriophage PRD1.
EMBO J. 1995 Dec 15;14(24):6078-86. doi: 10.1002/j.1460-2075.1995.tb00298.x.
7
Bacteriophage PRD1: a broad host range DSDNA tectivirus with an internal membrane.
Adv Virus Res. 1995;45:281-319. doi: 10.1016/s0065-3527(08)60064-0.
8
Phylogenetic analysis of the genera Alteromonas, Shewanella, and Moritella using genes coding for small-subunit rRNA sequences and division of the genus Alteromonas into two genera, Alteromonas (emended) and Pseudoalteromonas gen. nov., and proposal of twelve new species combinations.
Int J Syst Bacteriol. 1995 Oct;45(4):755-61. doi: 10.1099/00207713-45-4-755.
9
Phosphorus nuclear magnetic resonance studies on the lipid-containing bacteriophage PM2+.
Biochemistry. 1980 Nov 11;19(23):5264-70. doi: 10.1021/bi00564a018.
10
Electron microscopy of cells infected with nonsense mutants of bacteriophage phi 6.
Virology. 1980 Nov;107(1):222-8. doi: 10.1016/0042-6822(80)90287-1.
Zotero 插件