Bulpitt C J, Hodes C, Everitt M G
Br J Ophthalmol. 1975 Dec;59(12):717-20. doi: 10.1136/bjo.59.12.717.
The intraocular and systemic blood pressure, height, weight, and haemoglobin were measured in 573 subjects over 60 years old from a general practice population. Intraocular pressure was positively and independently related to systemic blood pressure (P less than 0.0001) and obesity (P less than 0.01) as assessed by the ponderal index. Systolic pressure rather than diastolic or mean pressure was most closely correlated with intraocular pressure and it is suggested that the systolic head of pressure increases the filtrated fraction of aqueous humour to cause a small but sustained rise in intraocular pressure. It is also suggested that obesity may decrease the facility of aqueous outflow.
对来自普通人群的573名60岁以上受试者测量了眼内压和全身血压、身高、体重及血红蛋白。通过体重指数评估，眼内压与全身血压（P<0.0001）和肥胖（P<0.01）呈正相关且相互独立。收缩压而非舒张压或平均压与眼内压的相关性最为密切，提示收缩压水头增加房水滤过分数，导致眼内压出现小幅度但持续的升高。还提示肥胖可能降低房水流出易度。
