Patel Nita, Clement Marc
Department of Medicine/Dermatology, UCLA School of Medicine, Los Angeles, California, USA.
Dermatol Surg. 2002 Oct;28(10):942-5; discussion 945. doi: 10.1046/j.1524-4725.2002.02062.x.
Selective nonablative wrinkle reduction with low-fluence pulsed dye laser has been shown to provide cosmetic benefits by stimulating the production of dermal collagen. The clinical efficacy for improving the appearance of acne scarring using selective nonablative laser treatments has yet to be established.
To evaluate the improvement in the appearance and topography of acne scarring following application of a 585 nm pulsed dye laser with a temporal profile and pulse duration designed specifically to target healthy microvasculature in the dermis.
Ten patients (mean age 34.8 years) with Fitzpatrick skin types I-IV and shallow to moderately deep, saucerized facial acne scars were enrolled in a prospective trial to receive a single laser treatment of both cheeks. Patients were evaluated at 30, 60, 90, and 120 days to assess the degree of clinical improvement. The evaluation process included assessment of pre- and posttreatment photography by two independent observers, patient assessment surveys, and surface profilometry using silicone imprints in order to quantify the degree of clinical improvement.
All 10 patients reported visible cosmetic improvement in the treated areas while surface profilometry showed that, on average, the depth of the acne scars was reduced by 47.8%. No adverse effects of this treatment were reported.
The treatment of acne scars utilizing a 585 nm pulsed dye laser with a temporal profile and pulse duration designed specifically to target healthy microvasculature in the dermis may be a safe and effective noninvasive alternative for a natural result.
低能量脉冲染料激光选择性非剥脱性减少皱纹已被证明可通过刺激真皮胶原蛋白的生成带来美容益处。使用选择性非剥脱性激光治疗改善痤疮瘢痕外观的临床疗效尚未确定。
评估应用585nm脉冲染料激光治疗后痤疮瘢痕外观和形态的改善情况，该激光具有专门针对真皮中健康微血管的时间分布和脉冲持续时间。
10名年龄在34.8岁的Fitzpatrick皮肤分型为I-IV型、面部有浅至中度深度、碟形痤疮瘢痕的患者纳入一项前瞻性试验，接受双侧脸颊单次激光治疗。在30、60、90和120天时对患者进行评估，以评估临床改善程度。评估过程包括由两名独立观察者对治疗前后的照片进行评估、患者评估调查以及使用硅胶印记进行表面轮廓测量，以量化临床改善程度。
所有10名患者均报告治疗区域有明显的美容改善，而表面轮廓测量显示，痤疮瘢痕深度平均减少了47.8%。未报告该治疗的不良反应。
利用585nm脉冲染料激光治疗痤疮瘢痕，该激光具有专门针对真皮中健康微血管的时间分布和脉冲持续时间，可能是一种安全有效的非侵入性替代方法，可获得自然效果。
