Svendsen U G
Acta Pathol Microbiol Scand A. 1975 Sep;83(5):568-72. doi: 10.1111/j.1699-0463.1975.tb00169.x.
The degree of round cell infiltration around hypertensively damaged heart arteries in one kidney Goldblatt hypertensive mice is more pronounced in haired mice with normal thymus function than in their nude littermates with genetic aplasia of the thymus. The level of hypertension and the prognoses for the hypertensive mice are, however, not influenced by the presence of thymus and thymus derived T cells. The results give evidence that delayed type immune reactions are involved in the hypertensive vascular disease in mice, but fail to support the assumption that they have pathogenic importance for either the level of hypertension or the prognoses of the one kidney Goldblatt hypertensive mice.
在一侧肾性高血压的戈德布拉特小鼠中，高血压性损伤的心脏动脉周围的圆形细胞浸润程度，在具有正常胸腺功能的有毛小鼠中比在胸腺发生遗传性发育不全的同窝裸鼠中更为明显。然而，高血压小鼠的高血压水平和预后不受胸腺及胸腺衍生的T细胞的影响。这些结果表明，迟发型免疫反应参与了小鼠的高血压血管疾病，但不支持这样的假设，即它们对一侧肾性高血压小鼠的高血压水平或预后具有致病重要性。
