Hilari Katerina, Byng Sally, Lamping Donna L, Smith Sarah C
Department of Language and Communication Science, Institute of Health, City University, Northampton Square, London EC1V 0HB, UK.
Stroke. 2003 Aug;34(8):1944-50. doi: 10.1161/01.STR.0000081987.46660.ED. Epub 2003 Jul 10.
Health-related quality of life (HRQL) is a key outcome in stroke clinical trials. Stroke-specific HRQL scales (eg, SS-QOL, SIS) have generally been developed with samples of stroke survivors that exclude people with aphasia. We adapted the SS-QOL for use with people with aphasia to produce the Stroke and Aphasia Quality of Life Scale (SAQOL). We report results from the psychometric evaluation of the initial 53-item SAQOL and the item-reduced SAQOL-39.
We studied 95 people with long-term aphasia to evaluate the acceptability, reliability, and validity of the SAQOL and SAQOL-39 using standard psychometric methods.
A total of 83 of 95 (87%) were able to complete the SAQOL by self-report; their results are reported here. Results supported the reliability and validity of the overall score on the 53-item SAQOL, but there was little support for hypothesized subdomains. Using factor analysis, we derived a shorter version (SAQOL-39) that identified 4 subdomains (physical, psychosocial, communication, and energy). The SAQOL-39 demonstrated good acceptability, internal consistency (Cronbach's alpha=0.74 to 0.94), test-retest reliability (intraclass correlation coefficient=0.89 to 0.98), and construct validity (corrected domain-total correlations, r=0.38 to 0.58; convergent, r=0.55 to 0.67; discriminant, r=0.02 to 0.27 validity).
The SAQOL-39 is an acceptable, reliable, and valid measure of HRQL in people with long-term aphasia. Further testing is needed to evaluate the responsiveness of the SAQOL-39 and to investigate its usefulness in evaluative research and routine clinical practice.
健康相关生活质量（HRQL）是中风临床试验的关键结果。特定于中风的HRQL量表（如SS - QOL、SIS）通常是在排除失语症患者的中风幸存者样本中开发的。我们对SS - QOL进行了调整，使其适用于失语症患者，从而产生了中风与失语症生活质量量表（SAQOL）。我们报告了最初的53项SAQOL和简化后的39项SAQOL - 39的心理测量评估结果。
我们研究了95名长期失语症患者，使用标准心理测量方法评估SAQOL和SAQOL - 39的可接受性、可靠性和有效性。
95名患者中有83名（87%）能够通过自我报告完成SAQOL；此处报告的是他们的结果。结果支持了53项SAQOL总分的可靠性和有效性，但对假设的子领域支持较少。通过因子分析，我们得出了一个较短的版本（SAQOL - 39），该版本确定了4个子领域（身体、心理社会、沟通和精力）。SAQOL - 39表现出良好的可接受性、内部一致性（克朗巴哈系数α = 0.74至0.94）、重测信度（组内相关系数 = 0.89至0.98）和结构效度（校正后的领域 - 总分相关性，r = 0.38至0.58；收敛效度，r = 0.55至0.67；区分效度，r = 0.02至0.27）。
SAQOL - 39是一种可接受、可靠且有效的长期失语症患者HRQL测量工具。需要进一步测试以评估SAQOL - 39的反应性，并研究其在评估研究和常规临床实践中的实用性。
