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1
Serotyping of cell culture-adapted subgroup 2 human rotavirus strains by neutralization.通过中和作用对细胞培养适应的2型人轮状病毒株进行血清分型
Infect Immun. 1984 Feb;43(2):722-9. doi: 10.1128/iai.43.2.722-729.1984.
2
Epidemiologic and genomic study of rotavirus strains infecting young children and calves in the same rural environment.对同一农村环境中感染幼儿和小牛的轮状病毒株进行的流行病学和基因组研究。
Eur J Epidemiol. 1986 Jun;2(2):108-11. doi: 10.1007/BF00157020.
3
Enzootic bovine rotavirus is not a source of infection in Panamanian cattle ranchers and their families.地方性牛轮状病毒不是巴拿马牧场主及其家人的感染源。
J Infect Dis. 1986 Jun;153(6):1139-44. doi: 10.1093/infdis/153.6.1139.
4
Independent segregation of two antigenic specificities (VP3 and VP7) involved in neutralization of rotavirus infectivity.参与轮状病毒感染性中和的两种抗原特异性（VP3和VP7）的独立分离。
Proc Natl Acad Sci U S A. 1985 Dec;82(24):8701-4. doi: 10.1073/pnas.82.24.8701.
5
Nucleotide sequence of UK bovine rotavirus segment 4: possible host restriction of VP3 genes.英国牛轮状病毒第4节段的核苷酸序列：VP3基因可能存在宿主限制
Virology. 1988 Oct;166(2):308-15. doi: 10.1016/0042-6822(88)90501-6.
6
Comparative analysis of the VP3 gene of divergent strains of the rotaviruses simian SA11 and bovine Nebraska calf diarrhea virus.猿猴SA11轮状病毒和牛内布拉斯加小牛腹泻病毒不同毒株VP3基因的比较分析。
J Virol. 1988 Nov;62(11):4022-6. doi: 10.1128/JVI.62.11.4022-4026.1988.
7
Seroconversion patterns to four human rotavirus serotypes in hospitalized infants with acute rotavirus gastroenteritis.急性轮状病毒胃肠炎住院婴儿中针对四种人类轮状病毒血清型的血清转化模式。
J Infect Dis. 1988 Sep;158(3):588-95. doi: 10.1093/infdis/158.3.588.
8
Prevalence of antibodies to rotavirus in different age-groups of infants in Bochum, West Germany.德国西部波鸿市不同年龄组婴儿轮状病毒抗体的流行情况。
J Infect Dis. 1988 May;157(5):1014-22. doi: 10.1093/infdis/157.5.1014.
9
Rotavirus gene structure and function.轮状病毒的基因结构与功能。
Microbiol Rev. 1989 Dec;53(4):410-49. doi: 10.1128/mr.53.4.410-449.1989.
10
RNA-RNA hybridization identifies a human rotavirus that is genetically related to feline rotavirus.RNA-RNA杂交鉴定出一种与猫轮状病毒存在基因关联的人类轮状病毒。
J Virol. 1989 Mar;63(3):1431-4. doi: 10.1128/JVI.63.3.1431-1434.1989.

厄瓜多尔和德国儿童中针对6型人类轮状病毒PA151和PA169的中和血清抗体

Neutralizing serum antibodies to serotype 6 human rotaviruses PA151 and PA169 in Ecuadorian and German children.

作者信息

Brüssow H, Gerna G, Sidoti J, Sarasini A

机构信息

Nestlé Research Centre, Nestec Ltd., Lausanne, Switzerland.

出版信息

J Clin Microbiol. 1992 Apr;30(4):911-4. doi: 10.1128/jcm.30.4.911-914.1992.

DOI:10.1128/jcm.30.4.911-914.1992
PMID:1315337
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC265184/
Abstract

Serum samples from 726 Ecuadorian children who underwent natural rotavirus (RV) exposure were tested for neutralizing serum antibodies against two serotype 6 (ST6) human RV (HRV) isolates from Italy, PA151 and PA169, and two ST6 bovine RV (BRV) isolates, NCDV and UK. Gene 4 was distinct in all four ST6 strains. Ninety-one, 56, 67, and 65 serum samples neutralized HRV PA151 (13%), HRV PA169 (8%), BRV NCDV (9%), and BRV UK (9%), respectively. A total of 44 of the 91 serum samples which neutralized HRV PA151 did not neutralize the other three ST6 RV strains. In addition, we identified three serum samples that neutralized HRV PA151 but none of the six human or four animal RV STs. However, we failed to identify serum samples that neutralized HRV PA169 without neutralizing at least one of the major HRV STs. With a hospital-based serum collection from German children (excluding gastroenteritis patients), we identified 3 out of 197 serum samples tested that neutralized HRV PA151 specifically, whereas none neutralized HRV PA169 exclusively. None of the 71 German infants hospitalized with primary RV gastroenteritis showed a PA151- or a PA169-specific antibody response.

摘要

对726名自然感染轮状病毒（RV）的厄瓜多尔儿童的血清样本进行检测，以分析其针对来自意大利的两株6型（ST6）人轮状病毒（HRV）分离株PA151和PA169以及两株ST6牛轮状病毒（BRV）分离株NCDV和UK的血清中和抗体。所有四株ST6毒株的基因4均不同。分别有91份、56份、67份和65份血清样本中和了HRV PA151（13%）、HRV PA169（8%）、BRV NCDV（9%）和BRV UK（9%）。在91份中和了HRV PA151的血清样本中，共有44份不能中和其他三株ST6 RV毒株。此外，我们鉴定出三份血清样本，它们能中和HRV PA151，但不能中和六株人源或四株动物源RV STs中的任何一株。然而，我们未能鉴定出能中和HRV PA169但不中和至少一种主要HRV STs的血清样本。在对德国儿童（不包括肠胃炎患者）进行的基于医院的血清采集检测中，我们在197份检测的血清样本中鉴定出3份能特异性中和HRV PA151的样本，而没有样本能单独中和HRV PA169。71名因原发性RV肠胃炎住院的德国婴儿均未表现出针对PA151或PA169的特异性抗体反应。