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The gene for proliferating cell nuclear antigen (Pcna) maps to mouse chromosome 2.

作者信息

Abbott C, Pilz A, Moseley H, Peter J

机构信息

Department of Genetics and Biometry, University College London, UK.

出版信息

Mamm Genome. 1992;3(5):286-9. doi: 10.1007/BF00292157.

Abstract

The structural gene for proliferating cell nuclear antigen (Pcna) has been mapped to mouse Chromosome (Chr) 2 by use of a PCR-based assay. With somatic cell hybrids, Pcna was mapped between the T(2;4)13H and T(2;4)1Sn breakpoints. An interspecific backcross was employed to map Pcna 1.9 +/- 1.3 cM distal to Il-lb. This was confirmed by mapping Pcna in the BXH recombinant inbred (RI) strains; no recombinants were seen between Il-la and Pcna. In addition, a PCNA-related sequence (Pcna-rsl) was mapped to Chr 19 in the BXH RI strains.

摘要

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