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SEROLOGICAL RESPONSES OF MAN TO TYPHOID VACCINES.人对伤寒疫苗的血清学反应。
Bull World Health Organ. 1964;30(5):653-62.
2
[EVALUATION OF VACCINES AND OF THE EFFECTIVENESS OF VACCINATIONS AGAINST TYPHOID FEVER. II. THE S. TYPHI ANTIBODY PICTURE IN THE POPULATION DESIGNATED FOR THE CONTROL OF ANTI-TYPHOID VACCINATION].[伤寒疫苗及伤寒疫苗接种效果评估。II. 用于伤寒疫苗接种对照人群中的伤寒杆菌抗体情况]
Przegl Epidemiol. 1963;17:13-21.
3
A CHALLENGE TO THE VALIDITY OF THE VI TEST FOR THE DETECTION OF CHRONIC TYPHOID CARRIERS.对用于检测慢性伤寒带菌者的Vi试验有效性的质疑。
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Specific and cross-reactive immune response to oral Salmonella Typhi Ty21a and parenteral Vi capsular polysaccharide typhoid vaccines administered concomitantly.对口服伤寒沙门氏菌Ty21a疫苗和肠外Vi荚膜多糖伤寒疫苗同时接种的特异性和交叉反应性免疫应答。
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THE PRESENT STATUS OF FIELD AND LABORATORY STUDIES OF TYPHOID AND PARATYPHOID VACCINES WITH SPECIAL REFERENCE TO STUDIES SPONSORED BY WORLD HEALTH ORGANIZATION.伤寒和副伤寒疫苗的现场及实验室研究现状，特别提及世界卫生组织资助的研究
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EVALUATION OF TYPHOID VACCINES IN THE LABORATORY AND IN A CONTROLLED FIELD TRIAL IN POLAND. PRELIMINARY REPORT.伤寒疫苗在实验室及波兰一项对照现场试验中的评估。初步报告。
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THE PRESENT STATUS OF FIELD AND LABORATORY STUDIES OF TYPHOID AND PARATYPHOID VACCINES WITH SPECIAL REFERENCE TO STUDIES SPONSORED BY WORLD HEALTH ORGANIZATION.伤寒和副伤寒疫苗的现场及实验室研究现状，特别提及世界卫生组织资助的研究
Bull World Health Organ. 1965;32(1):29-36.
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5
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8
Vaccines and cell-mediated immunity.疫苗与细胞介导免疫
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9
Reactions and serologic responses to monovalent acetone-inactivated typhoid vaccine and heat-killed TAB when given by jet injection.通过喷射注射给予单价丙酮灭活伤寒疫苗和热灭活伤寒、副伤寒甲、乙三联疫苗后的反应及血清学反应。
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10
Pathogenesis of typhoid fever.伤寒热的发病机制。
Indian J Pediatr. 1985 Jul-Aug;52(417):371-8. doi: 10.1007/BF02806620.

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A New Type of Typhoid and Paratyphoid Vaccine.一种新型伤寒和副伤寒疫苗。
Br Med J. 1941 Mar 15;1(4184):391-5. doi: 10.1136/bmj.1.4184.391.
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[Typhoid vaccine assay chicken embryo].伤寒疫苗鸡胚测定
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BASIS FOR IMMUNITY TO TYPHOID IN MICE AND THE QUESTION OF "CELLULAR IMMUNITY".小鼠对伤寒免疫的基础及“细胞免疫”问题
Bacteriol Rev. 1963 Dec;27(4):391-404. doi: 10.1128/br.27.4.391-404.1963.
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[EVALUATION OF VACCINES AND OF THE EFFECTIVENESS OF VACCINATIONS AGAINST TYPHOID FEVER. IX. USE OF THE PHAGOCYTESIS TEST IN THE EVALUATION OF THE EFFECTIVENESS OF VACCINATIONS AGAINST TYPHOID FEVER. (PRELIMINARY COMMUNICATION)].[伤寒疫苗及伤寒疫苗接种效果的评估。IX. 吞噬作用试验在伤寒疫苗接种效果评估中的应用。（初步报告）]
Przegl Epidemiol. 1963;17:63-70.
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[EVALUATION OF VACCINES AND OF THE EFFECTIVENESS OF VACCINATIONS AGAINST TYPHOID FEVER. VIII. SEROLOGICAL REACTIONS IN SUBJECTS VACCINATED WITH VARIOUS ANTITYPHOID VACCINES].[伤寒疫苗及伤寒疫苗接种效果的评估。VIII. 接种各种伤寒疫苗的受试者的血清学反应]
Przegl Epidemiol. 1963;17:55-62.
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[EVALUATION OF VACCINES AND THE EFFECTIVENESS OF VACCINATIONS AGAINST TYPHOID FEVER. III. SELECTION AND PRELIMINARY CHARACTERISTICS OF VACCINES DESIGNATED FOR CONTROL VACCINATIONS].[伤寒疫苗评估及伤寒疫苗接种效果。III. 用于对照接种的疫苗的选择及初步特性]
Przegl Epidemiol. 1963;17:23-32.
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Studies on infection and immunity in experimental typhoid fever. IV. Role of H antigen in protection.实验性伤寒热感染与免疫研究。IV. H抗原在保护中的作用。
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[Immunological study of combined antidiphtheritic, antitetanic, antityphoparatyphoid and antipoliomyelitic vaccinaction].[白喉、破伤风、伤寒副伤寒及脊髓灰质炎联合疫苗接种的免疫学研究]
Bull World Health Organ. 1962;26(6):699-725.
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Laboratory tests of typhoid vaccines used in a controlled field study.在一项对照现场研究中使用的伤寒疫苗的实验室检测。
Bull World Health Organ. 1959;20(6):1017-32.
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H antigen of Salmonella typhosa.伤寒沙门氏菌的H抗原。
J Bacteriol. 1961 Jun;81(6):924-32. doi: 10.1128/jb.81.6.924-932.1961.

人对伤寒疫苗的血清学反应。

SEROLOGICAL RESPONSES OF MAN TO TYPHOID VACCINES.

作者信息

BENENSON A S

出版信息

Bull World Health Organ. 1964;30(5):653-62.

PMID:14196813
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2554993/
Abstract

Study of the serological responses in man to typhoid vaccines tested in several WHO-sponsored controlled field trials in British Guiana, Poland and Yugoslavia has not indicated any correlation between the level of Vi and O antibodies elicited and the effectiveness of the vaccines. Instead, the more effective vaccines have elicited significantly greater H-antibody responses; but a variety of factors suggests that it may in fact not be the antibody that confers immunity to the disease. The phagocytic test does not appear promising as a technique for determining the effectiveness of a typhoid vaccine, but passive protection of the chick-embryo may warrant further investigation.

摘要

在英属圭亚那、波兰和南斯拉夫进行的多项由世界卫生组织赞助的对照现场试验中，对人体针对伤寒疫苗的血清学反应进行的研究表明，所引发的Vi抗体和O抗体水平与疫苗的有效性之间没有任何关联。相反，更有效的疫苗引发了显著更强的H抗体反应；但多种因素表明，实际上赋予疾病免疫力的可能并非抗体。吞噬试验作为一种确定伤寒疫苗有效性的技术似乎前景不佳，但鸡胚的被动保护可能值得进一步研究。