• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

某些双-5-甲基苯并咪唑化合物的抗真菌活性

Antifungal activity of some bis-5-methylbenzimidazole compounds.

作者信息

Küçükbay H, Durmaz R, Okyucu N, Günal S

机构信息

Department of Chemistry, Faculty of Arts and Sciences, Inönü University, 44069 Malatya, Turkey.

出版信息

Folia Microbiol (Praha). 2003;48(5):679-81. doi: 10.1007/BF02993478.

DOI:10.1007/BF02993478
PMID:14976728
Abstract

Twenty bis-5-methylbenzimidazole compounds were evaluated for their in vitro antifungal activity against Candida albicans and Candida tropicalis. Except for three all compounds exhibited an antifungal activity against these yeasts over a range of the minimum inhibitory concentration (MIC) between 25 and 800 mg/L.

摘要

评估了20种双-5-甲基苯并咪唑化合物对白色念珠菌和热带念珠菌的体外抗真菌活性。除三种化合物外,所有化合物对这些酵母均表现出抗真菌活性,最低抑菌浓度(MIC)范围在25至800mg/L之间。

相似文献

1
Antifungal activity of some bis-5-methylbenzimidazole compounds.某些双-5-甲基苯并咪唑化合物的抗真菌活性
Folia Microbiol (Praha). 2003;48(5):679-81. doi: 10.1007/BF02993478.
2
1,2,4-Triazolo mercapto and aminonitriles as potent antifungal agents.
Bioorg Med Chem Lett. 2003 Aug 4;13(15):2601-5. doi: 10.1016/s0960-894x(03)00378-0.
3
Evaluation of the "Dip Effect" Phenomenon in Antifungal Susceptibility Testing of Candida spp. against Echinocandins by Use of Gradient Concentration Strips.使用梯度浓度条评估念珠菌属对棘白菌素类抗真菌药敏试验中的“拖尾效应”现象
J Clin Microbiol. 2015 Nov;53(11):3654-9. doi: 10.1128/JCM.02073-15. Epub 2015 Sep 2.
4
In vitro antifungal activity of the flavonoid baicalein against Candida species.黄酮类化合物黄芩素对念珠菌属的体外抗真菌活性。
J Med Microbiol. 2012 Dec;61(Pt 12):1704-1708. doi: 10.1099/jmm.0.047852-0. Epub 2012 Aug 23.
5
Anti-Candida and mode of action of two newly synthesized polymers: a modified poly (methylmethacrylate-co-vinylbenzoylchloride) and a modified linear poly (chloroethylvinylether-co-vinylbenzoylchloride) with special reference to Candida albicans and Candida tropicalis.两种新合成聚合物的抗念珠菌活性及作用方式:一种改性聚(甲基丙烯酸甲酯-共-乙烯基苯甲酰氯)和一种改性线性聚(氯乙基乙烯基醚-共-乙烯基苯甲酰氯),特别针对白色念珠菌和热带念珠菌 。
Mycopathologia. 2004 Feb;157(2):145-53. doi: 10.1023/b:myco.0000020593.75809.91.
6
Structure-activity relationship study of nitrosopyrimidines acting as antifungal agents.硝基亚嘧啶类化合物作为抗真菌剂的构效关系研究。
Bioorg Med Chem. 2012 Oct 15;20(20):6109-22. doi: 10.1016/j.bmc.2012.08.033. Epub 2012 Aug 31.
7
Brief exposure to antimycotics reduces the extracellular phospholipase activity of Candida albicans and Candida tropicalis.短期接触抗真菌药可降低白色念珠菌和热带念珠菌的细胞外磷脂酶活性。
Chemotherapy. 2003 Sep;49(5):243-7. doi: 10.1159/000072448.
8
Antifungal activity of silver nanoparticles obtained by green synthesis.通过绿色合成法制备的银纳米颗粒的抗真菌活性。
Rev Inst Med Trop Sao Paulo. 2015 Mar-Apr;57(2):165-7. doi: 10.1590/S0036-46652015000200011.
9
Spermidine-analogous triamines suppressed the growth of Candida albicans.亚精胺类似的三胺抑制白色念珠菌的生长。
Biol Pharm Bull. 2013;36(9):1440-7. doi: 10.1248/bpb.b13-00148.
10
[Susceptibility to fluconazole of clinical interest yeasts: new breakpoints].[具有临床意义的酵母对氟康唑的敏感性:新的折点]
Rev Esp Quimioter. 2012 Dec;25(4):266-8.

引用本文的文献

1
1-(Prop-2-en-1-yl)-3-[(trimethyl-sil-yl)meth-yl]benzimidazolium bromide monohydrate.1-(2-丙烯-1-基)-3-[(三甲基硅基)甲基]苯并咪唑溴化物一水合物
Acta Crystallogr Sect E Struct Rep Online. 2010 Aug 25;66(Pt 9):o2393-4. doi: 10.1107/S1600536810033015.
2
1-Benzyl-3-[(trimethyl-sil-yl)meth-yl]benzimidazolium chloride monohydrate.1-苄基-3-[(三甲基硅基)甲基]苯并咪唑鎓氯化物一水合物
Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 26;66(Pt 7):o1770-1. doi: 10.1107/S1600536810024128.
3
Antimicrobial activity of ZnII, CdII, and HgII complexes of 1,2-bis-[2-(5-R)-1H-benzimidazolyl]-1,2-ethanediols and 1,4-bis-[2-(5-R)-1H-benzimidazolyl]-1,2,3,4-butanetetraols.

本文引用的文献

1
Synthesis and antibacterial activities of new bis-benzimidazoles.新型双苯并咪唑的合成及其抗菌活性
Arzneimittelforschung. 2004;54(1):64-8. doi: 10.1055/s-0031-1296938.
2
Antimicrobial activity of FeIII, CuII, AgI, ZnII and HgII complexes of 2-(2-hydroxy-5-bromo/nitro-phenyl)-1H- and 2-(2-hydroxyphenyl)-5-methyl/chloro/nitro-1H-benzimidazoles.2-(2-羟基-5-溴/硝基苯基)-1H-和2-(2-羟基苯基)-5-甲基/氯/硝基-1H-苯并咪唑的铁(III)、铜(II)、银(I)、锌(II)和汞(II)配合物的抗菌活性
Folia Microbiol (Praha). 2002;47(5):481-7. doi: 10.1007/BF02818785.
3
In vitro antimicrobial activity of 3,4-dihydro-s-triazinobenzimidazole derivatives.
1,2-双-[2-(5-R)-1H-苯并咪唑基]-1,2-乙二醇和1,4-双-[2-(5-R)-1H-苯并咪唑基]-1,2,3,4-丁四醇的锌(II)、镉(II)和汞(II)配合物的抗菌活性
Folia Microbiol (Praha). 2005;50(6):473-8. doi: 10.1007/BF02931432.
4
Antimicrobial activity of 1,2-bis-[2-(5-R)-1H-benzimidazolyl]- 1,2-ethanediols, 1,4-bis-[2-(5-R)-1H-benzimidazolyl]- 1,2,3,4-butanetetraols and their FeIII, CuII, and AgI complexes.1,2-双-[2-(5-R)-1H-苯并咪唑基]-1,2-乙二醇、1,4-双-[2-(5-R)-1H-苯并咪唑基]-1,2,3,4-丁四醇及其铁(III)、铜(II)和银(I)配合物的抗菌活性
Folia Microbiol (Praha). 2005;50(6):467-72. doi: 10.1007/BF02931431.
3,4-二氢-s-三嗪苯并咪唑衍生物的体外抗菌活性
Folia Microbiol (Praha). 2002;47(1):29-31. doi: 10.1007/BF02818561.
4
Synthesis of some benzimidazole derivatives and their antibacterial and antifungal activities.一些苯并咪唑衍生物的合成及其抗菌和抗真菌活性。
Arzneimittelforschung. 2001;51(5):420-4. doi: 10.1055/s-0031-1300057.
5
Structure-in vitro activity relationships of pentamidine analogues and dication-substituted bis-benzimidazoles as new antifungal agents.喷他脒类似物和二价阳离子取代的双苯并咪唑作为新型抗真菌剂的结构-体外活性关系
Antimicrob Agents Chemother. 1998 Oct;42(10):2495-502. doi: 10.1128/AAC.42.10.2495.
6
Anti-Pneumocystis activities of aromatic diamidoxime prodrugs.芳香二脒肟前药的抗肺孢子菌活性。
Antimicrob Agents Chemother. 1998 Mar;42(3):666-74. doi: 10.1128/AAC.42.3.666.
7
Antifungal activity of organic and organometallic derivatives of benzimidazole and benzothiazole.苯并咪唑和苯并噻唑的有机及有机金属衍生物的抗真菌活性
Arzneimittelforschung. 1997 May;47(5):667-70.
8
Antimicrobial activity of carbene complexes of rhodium(I) and ruthenium(II).铑(I)和钌(II)卡宾配合物的抗菌活性
Arzneimittelforschung. 1996 Aug;46(8):821-3.
9
Synthesis of some hydroxamic acid derivatives of benzimidazole and their antibacterial and antifungal activities.苯并咪唑的一些异羟肟酸衍生物的合成及其抗菌和抗真菌活性。
Arzneimittelforschung. 1992 Aug;42(8):1045-8.