3,4-二氢-s-三嗪苯并咪唑衍生物的体外抗菌活性
In vitro antimicrobial activity of 3,4-dihydro-s-triazinobenzimidazole derivatives.
作者信息
Gulyás G, Emri T, Simon A, Györgydeák Z
机构信息
Department of Organic Chemistry, Faculty of Science, University of Debrecen, 4010 Debrecen, Hungary.
出版信息
Folia Microbiol (Praha). 2002;47(1):29-31. doi: 10.1007/BF02818561.
PMID:11980265
Abstract
Among 31 3,4-dihydro-s-triazinobenzimidazole derivatives tested 12 compounds showed in vitro antimicrobial activity against G+ bacteria. Best results were obtained with substances containing naphthyl or halogenated phenyl group on the triazine ring. The tested derivatives had no significant in vitro antimicrobial activity against either the used G- species or fungi.
摘要
在测试的31种3,4-二氢-s-三嗪苯并咪唑衍生物中，有12种化合物对革兰氏阳性菌表现出体外抗菌活性。在三嗪环上含有萘基或卤代苯基的物质取得了最佳结果。所测试的衍生物对所用的革兰氏阴性菌或真菌均无显著的体外抗菌活性。
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