Lattif Ali Abdul, Banerjee Uma, Prasad Rajendra, Biswas Ashutosh, Wig Naveet, Sharma Neeraj, Haque Absarul, Gupta Nivedita, Baquer Najma Z, Mukhopadhyay Gauranga
School of Life Sciences, Jawaharlal Nehru University, New Delhi, India.
J Clin Microbiol. 2004 Mar;42(3):1260-2. doi: 10.1128/JCM.42.3.1260-1262.2004.
A study of oropharyngeal candidiasis (OPC) in Indian human immunodeficiency virus (HIV)/AIDS patients was conducted over a period of 15 months. This study revealed that 75% of the HIV/AIDS patients had OPC. MIC testing revealed that 5% of the Candida isolates were fluconazole resistant. A correlation between CD4(+)-T-cell counts and development of OPC in HIV/AIDS patients was also observed. Molecular typing of C. albicans isolates showed that all were genetically unrelated.
对印度人类免疫缺陷病毒(HIV)/艾滋病患者的口腔念珠菌病(OPC)进行了为期15个月的研究。该研究显示,75%的HIV/艾滋病患者患有OPC。最低抑菌浓度(MIC)测试显示,5%的念珠菌分离株对氟康唑耐药。还观察到HIV/艾滋病患者的CD4(+) - T细胞计数与OPC发病之间的相关性。白色念珠菌分离株的分子分型显示,所有分离株在基因上均无关联。