德国耐红霉素化脓性链球菌分离株的克隆相关性
Clonal relatedness of erythromycin-resistant Streptococcus pyogenes isolates in Germany.
作者信息
Reinert Ralf R, Lütticken Rudolf, Sutcliffe Joyce A, Tait-Kamradt Amelia, Cil Murat Y, Schorn Holger M, Bryskier André, Al-Lahham Adnan
机构信息
Institute for Medical Microbiology, National Reference Center for Streptococci, University Hospital, D-52057 Aachen, Germany.
出版信息
Antimicrob Agents Chemother. 2004 Apr;48(4):1369-73. doi: 10.1128/AAC.48.4.1369-1373.2004.
Abstract
In a nationwide study in Germany, a total of 381 Streptococcus pyogenes were collected. Erythromycin A-resistant strains were characterized for the underlying resistance genotype, showing 55.6% had the efflux type mef(A), 31.5% had erm(A), and 13.0% had erm(B). A total of 23 different multilocus sequence types were observed.
摘要
在德国的一项全国性研究中，共收集了381株化脓性链球菌。对红霉素A耐药菌株进行了潜在耐药基因型鉴定，结果显示55.6%具有外排型mef(A)，31.5%具有erm(A)，13.0%具有erm(B)。共观察到23种不同的多位点序列类型。
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