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本文引用的文献

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Multilocus restriction typing: a tool for Neisseria meningitidis strain discrimination.多位点限制性酶切分型：一种用于鉴别脑膜炎奈瑟菌菌株的工具。
J Med Microbiol. 2003 Sep;52(Pt 9):781-787. doi: 10.1099/jmm.0.05225-0.
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Denaturing gradient gel electrophoretic multilocus sequence typing of Staphylococcus aureus isolates.金黄色葡萄球菌分离株的变性梯度凝胶电泳多位点序列分型
Electrophoresis. 2002 Sep;23(19):3310-20. doi: 10.1002/1522-2683(200210)23:19<3310::AID-ELPS3310>3.0.CO;2-O.
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Molecular epidemiological analysis of the changing nature of a meningococcal outbreak following a vaccination campaign.疫苗接种运动后脑膜炎球菌暴发性质变化的分子流行病学分析
J Clin Microbiol. 2002 Oct;40(10):3565-71. doi: 10.1128/JCM.40.10.3565-3571.2002.
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A comparison of multilocus sequence typing and fluorescent fragment-length polymorphism analysis genotyping of clone complex and other strains of Neisseria meningitidis.多位点序列分型与荧光片段长度多态性分析对脑膜炎奈瑟菌克隆复合体及其他菌株进行基因分型的比较
J Med Microbiol. 2001 Nov;50(11):991-995. doi: 10.1099/0022-1317-50-11-991.
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Semiautomation of multilocus sequence typing for the characterization of clinical isolates of Neisseria meningitidis.用于脑膜炎奈瑟菌临床分离株特征鉴定的多位点序列分型半自动化方法
J Clin Microbiol. 2001 Sep;39(9):3066-71. doi: 10.1128/JCM.39.9.3066-3071.2001.
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Fluorescent amplified-fragment length polymorphism genotyping of Neisseria meningitidis identifies clones associated with invasive disease.脑膜炎奈瑟菌的荧光扩增片段长度多态性基因分型可鉴定出与侵袭性疾病相关的克隆。
J Clin Microbiol. 2000 Dec;38(12):4580-5. doi: 10.1128/JCM.38.12.4580-4585.2000.
7
Multilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganisms.多位点序列分型：一种用于鉴定致病微生物群体内克隆的便捷方法。
Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3140-5. doi: 10.1073/pnas.95.6.3140.
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New Zealand epidemic of meningococcal disease identified by a strain with phenotype B:4:P1.4.通过B:4:P1.4表型菌株确定的新西兰脑膜炎球菌病疫情。
J Infect Dis. 1998 Feb;177(2):497-500. doi: 10.1086/517385.
9
Clonal population structure of Neisseria meningitidis serogroup A isolated from epidemics and pandemics between 1915 and 1983.1915年至1983年间从流行性和大流行性疫情中分离出的A群脑膜炎奈瑟菌的克隆群体结构。
Rev Infect Dis. 1987 Jul-Aug;9(4):665-92. doi: 10.1093/clinids/9.4.665.
10
Clones of serogroup B Neisseria meningitidis causing systemic disease in The Netherlands, 1958-1986.1958年至1986年在荷兰引起全身性疾病的B群脑膜炎奈瑟菌克隆
J Infect Dis. 1990 Oct;162(4):867-74. doi: 10.1093/infdis/162.4.867.

预测脑膜炎球菌序列类型的多位点限制性酶切分型方法。

Multilocus restriction typing method to predict the sequence type of meningococci.

作者信息

Dyet Kristin H, Simmonds Robin S, Martin Diana R

机构信息

Communicable Disease Group, ESR Ltd., Porirua, New Zealand.

出版信息

J Clin Microbiol. 2004 Apr;42(4):1742-5. doi: 10.1128/JCM.42.4.1742-1745.2004.

DOI:10.1128/JCM.42.4.1742-1745.2004
PMID:15071037
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC387554/
Abstract

A multilocus restriction typing (MLRT) method was developed to reduce the number of sequencing reactions required to determine the clonal relationships among serogroup B meningococci causing an epidemic in New Zealand. MLRT was a rapid, simple, and inexpensive method, and the results had an excellent correlation with multilocus sequence typing results.

摘要

开发了一种多位点限制性分型（MLRT）方法，以减少确定在新西兰引发疫情的B群脑膜炎奈瑟菌之间克隆关系所需的测序反应数量。MLRT是一种快速、简单且廉价的方法，其结果与多位点序列分型结果具有极好的相关性。