Ribes G, Valette G, Lignon F, Loubatières-Mariani M M
C R Seances Soc Biol Fil. 1978;172(1):161-6.
In the normal anesthetized dog, the endogenous hyperlactatemia induced either by intense muscular work or by a high dose of phenformin (20 mg/kg subtucaneously) is followed by an increase in the pancreaticoduodenal insulin output. A previous perfusion of sodium dichloroacetate (50 mg/kg. h) opposes the hyperlactatemia, and reduces or suppresses the increase in insulin output.
在正常麻醉犬中，由剧烈肌肉运动或高剂量苯乙双胍（20毫克/千克皮下注射）诱导的内源性高乳酸血症之后，胰十二指肠胰岛素分泌增加。先前灌注二氯醋酸钠（50毫克/千克·小时）可对抗高乳酸血症，并减少或抑制胰岛素分泌的增加。
