从匈牙利一株耐碳青霉烯类铜绿假单胞菌临床分离株中分离出携带整合子的blaVIM-4型金属β-内酰胺酶基因。
Isolation of an integron-borne blaVIM-4 type metallo-beta-lactamase gene from a carbapenem-resistant Pseudomonas aeruginosa clinical isolate in Hungary.
作者信息
Libisch Balázs, Gacs Mária, Csiszár Károly, Muzslay Mónika, Rókusz László, Füzi Miklós
机构信息
Department of Bacteriology, National Center for Epidemiology, 1097 Budapest, Gyáli út 2-6, Hungary.
出版信息
Antimicrob Agents Chemother. 2004 Sep;48(9):3576-8. doi: 10.1128/AAC.48.9.3576-3578.2004.
Abstract
The first integron-borne metallo-beta-lactamase gene was isolated in Hungary. The bla(VIM-4) gene is located on a class 1 integron that also carries a novel bla(OXA)-like gene. The integron is harbored by a serotype O12 Pseudomonas aeruginosa strain and shows high structural similarity to integrons isolated in Greece and Poland.
摘要
首个整合子携带的金属β-内酰胺酶基因是在匈牙利分离得到的。bla(VIM-4)基因位于1类整合子上，该整合子还携带一个新的bla(OXA)样基因。该整合子存在于一株O12血清型铜绿假单胞菌菌株中，与在希腊和波兰分离得到的整合子具有高度的结构相似性。
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