Sautour Marc, Mitaine-Offer Anne-Claire, Miyamoto Tomofumi, Wagner Hildebert, Lacaille-Dubois Marie-Aleth
Laboratoire de Pharmacognosie, Unité UMIB, EA 3660, Faculté de Pharmacie, Université de Bourgogne, Dijon, France.
Chem Pharm Bull (Tokyo). 2004 Oct;52(10):1235-7. doi: 10.1248/cpb.52.1235.
Phytochemical investigation of the rhizome of Dioscorea opposita has led to the isolation of a new phenanthrene glycoside, 3,4,6-trihydroxyphenanthrene-3-O-beta-D-glucopyranoside (1), and five known compounds, soyacerebroside I (2), adenosine (3), beta-sitosterol (4), palmitic acid (5) and palmitoyloleoylphosphatidylcholine (6). Their structures were determined by spectroscopic methods, including 1D- and 2D-NMR. Compounds 1-6 exhibited no antifungal activity against the human pathogenic yeasts Candida albicans, C. glabrata and C. tropicalis.
对山药根茎进行植物化学研究，从中分离出一种新的菲糖苷，即3,4,6 - 三羟基菲 - 3 - O - β - D - 吡喃葡萄糖苷（1），以及五种已知化合物，大豆脑苷脂I（2）、腺苷（3）、β - 谷甾醇（4）、棕榈酸（5）和棕榈酰油酰磷脂酰胆碱（6）。通过包括一维和二维核磁共振在内的光谱方法确定了它们的结构。化合物1 - 6对人类致病酵母白色念珠菌、光滑念珠菌和热带念珠菌均无抗真菌活性。
