Griffiths C E, Wang T S, Hamilton T A, Voorhees J J, Ellis C N
Department of Dermatology, University of Michigan Medical Center, Ann Arbor 48109-0314.
Arch Dermatol. 1992 Mar;128(3):347-51.
The assessment of the severity of cutaneous photodamage and its response to treatment is an impractical consideration for most practitioners without extensive experience or recourse to high-quality, standardized, baseline photographs. To address this problem, a nine-point photonumeric standard scale was developed using photographs of subjects representing grades of photodamage from none to severe. This scale was formally tested in a side-by-side comparison with a conventional and widely used written descriptive scale. A panel of seven graders used both scales to score two sets of 25 photographs of photodamaged individuals, and the intergrader agreement and repeatability for the scales were calculated.
The photonumeric scale demonstrated significantly greater agreement between graders than did the descriptive scale (chance-corrected agreements of 0.31 and 0.11, respectively, P less than .0001) with no significant difference in repeatability between the two methods.
This study demonstrates that the photonumeric standard scale is superior to existing methodology in the accurate assessment of cutaneous photodamage and would be a useful adjunct to studies of the efficacy of skin repair agents for this indication.
对于大多数没有丰富经验或无法获取高质量、标准化基线照片的从业者而言，评估皮肤光损伤的严重程度及其对治疗的反应是一项不切实际的考量。为解决这一问题，利用代表从无到严重不同光损伤等级的受试者照片，制定了一个九点光子数字标准量表。该量表与传统且广泛使用的书面描述性量表进行了并列比较的正式测试。一组七名评分者使用这两种量表对两组共25张光损伤个体的照片进行评分，并计算了量表的评分者间一致性和可重复性。
光子数字量表在评分者之间显示出比描述性量表更高的一致性（校正机遇一致性分别为0.31和0.11，P<0.0001），两种方法在可重复性方面无显著差异。
本研究表明，光子数字标准量表在准确评估皮肤光损伤方面优于现有方法，对于研究该适应症皮肤修复剂的疗效将是一个有用的辅助工具。
