一种无创隐形眼镜葡萄糖传感器的临床试验。
Clinical trial of a noninvasive contact lens glucose sensor.
作者信息
March Wayne F, Mueller Achim, Herbrechtsmeier Peter
机构信息
Department of Ophthalmology, Downstate Health Science Center, State University of New York, Brooklyn, New York 11203-2098, USA.
出版信息
Diabetes Technol Ther. 2004 Dec;6(6):782-9. doi: 10.1089/dia.2004.6.782.
OBJECTIVE
The purpose of the present study was to determine the effectiveness of a fluorescent contact lens glucose sensor in monitoring glucose in patients with diabetes.
METHODS
Under an institutional review board-approved protocol, five fasting patients with type II diabetes were given a challenge consisting of 75 mL of Sustacal (Thomson Micromedex, Greenwood, CO) by mouth. Contact lens fluorescence and venous blood glucose were measured over a 3-h period.
RESULTS
Contact lens fluorescence appeared to track blood glucose well. The fluorescent daily-wear disposable contact lenses were comfortable and were tolerated well, even in patients who had not previously worn contact lenses.
CONCLUSION
The contact lens glucose sensor shows promise as a home glucose monitor.
目的
本研究的目的是确定荧光隐形眼镜葡萄糖传感器在监测糖尿病患者血糖方面的有效性。
方法
在机构审查委员会批准的方案下，五名空腹的II型糖尿病患者口服75毫升的苏适宝（Thomson Micromedex，格林伍德，科罗拉多州）进行激发试验。在3小时内测量隐形眼镜荧光和静脉血糖。
结果
隐形眼镜荧光似乎能很好地跟踪血糖。这种荧光日抛型一次性隐形眼镜佩戴舒适，即使是以前从未戴过隐形眼镜的患者也能很好地耐受。
结论
隐形眼镜葡萄糖传感器有望成为一种家用血糖监测仪。
Zotero 插件