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对机械通气新生儿气管吸出物的显微镜观察。II. 支气管肺发育不良的发病及其他变化。

Microscopic observations on tracheal aspirates from ventilated neonates. II. The onset of bronchopulmonary dysplasia and other changes.

作者信息

Jacobson W, Morley C J, South M

机构信息

University of Cambridge, Department of Paediatrics, Addenbrooke's Hospital, United Kingdom.

出版信息

Eur J Pediatr. 1992 Mar;151(3):204-7. doi: 10.1007/BF01954385.

DOI:10.1007/BF01954385
PMID:1601013
Abstract

A total of 450 undiluted and unprocessed tracheal aspirates from 120 intubated infants were examined microscopically for evidence of bronchopulmonary dysplasia and other changes. In 19 infants desquamated sheets of dysplastic epithelium in the fresh aspirate provided an early indication of developing bronchopulmonary dysplasia. Examination of unstained tracheal aspirates can provide, within minutes, information not only about the onset and development of bronchopulmonary dysplasia, but also provide evidence for milk or formula aspiration and for gastro-oesophageal reflux.

摘要

对120名插管婴儿的450份未经稀释和处理的气管吸出物进行了显微镜检查，以寻找支气管肺发育不良及其他变化的证据。在19名婴儿的新鲜吸出物中，发育异常的上皮细胞脱屑片为支气管肺发育不良的发展提供了早期迹象。对未染色的气管吸出物进行检查，不仅可以在几分钟内提供有关支气管肺发育不良的发生和发展的信息，还可以提供牛奶或配方奶误吸以及胃食管反流的证据。

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Eur J Pediatr. 1992 Mar;151(3):204-7. doi: 10.1007/BF01954385.
2
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本文引用的文献

1
Newborn tracheal aspirate cytology: classification during respiratory distress syndrome and bronchopulmonary dysplasia.新生儿气管吸出物细胞学检查：呼吸窘迫综合征和支气管肺发育不良期间的分类
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Cytologic evaluation of pulmonary effluent in neonates with respiratory distress syndrome and bronchopulmonary dysplasia.患有呼吸窘迫综合征和支气管肺发育不良的新生儿肺流出物的细胞学评估。
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The injurious effect of neutrophils on pneumocytes in vitro.
中性粒细胞在体外对肺细胞的损伤作用。
Am Rev Respir Dis. 1984 Jun;129(6):964-73. doi: 10.1164/arrd.1984.129.6.964.
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Lipid-laden macrophages in tracheal aspirates of newborn infants receiving intravenous lipid infusions: a cytologic study.
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Neonatal lung neutrophils and elastase/proteinase inhibitor imbalance.新生儿肺中性粒细胞与弹性蛋白酶/蛋白酶抑制剂失衡。
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Concentrations of alpha 1-proteinase inhibitor and alpha 2-macroglobulin in serum and lung secretions of intubated infants.插管婴儿血清和肺分泌物中α1-蛋白酶抑制剂和α2-巨球蛋白的浓度。
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Fibrotic reactions in the lung: the activation of the lung fibroblast.肺中的纤维化反应：肺成纤维细胞的激活。
Exp Lung Res. 1986;11(4):245-61. doi: 10.3109/01902148609062828.
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Tracheal aspirates from neonates during endotracheal intubation: detection of surfactant by polarized light microscopy.新生儿气管插管期间气管吸出物：通过偏振光显微镜检测表面活性剂
J Pediatr. 1988 Aug;113(2):368-72. doi: 10.1016/s0022-3476(88)80286-5.