• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

中东脑炎患者脑脊液中单纯疱疹病毒（1型和2型）、水痘-带状疱疹病毒、巨细胞病毒以及人类疱疹病毒6型和7型DNA的流行情况

Prevalence of herpes simplex virus (types 1 and 2), varicella-zoster virus, cytomegalovirus, and human herpesvirus 6 and 7 DNA in cerebrospinal fluid of Middle Eastern patients with encephalitis.

作者信息

Ibrahim Ali I, Obeid Michel T, Jouma Muhidien J, Roemer Klaus, Mueller-Lantzsch Nikolaus, Gärtner Barbara C

机构信息

Department of Clinical Chemistry and Microbiology, University of Damascus, Syria.

出版信息

J Clin Microbiol. 2005 Aug;43(8):4172-4. doi: 10.1128/JCM.43.8.4172-4174.2005.

DOI:10.1128/JCM.43.8.4172-4174.2005
PMID:16081968
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1233955/
Abstract

HSV-1 DNA was detected in 32 (30%) of 106 cerebrospinal fluid samples from patients with encephalitis. Cytomegalovirus, varicella-zoster virus, and human herpesvirus 6 (HHV-6) DNAs were each detected in three patients (3%); herpes simplex virus type 2 (HSV-2) and HHV-7 PCRs were negative. HSV detection was associated with seizure (P = 0.02), especially focal seizure (P = 0.0002), and pathological computed tomography (P = 0.02) with focal lesions (P = 0.0004).

摘要

在106例脑炎患者的脑脊液样本中，32例（30%）检测到单纯疱疹病毒1型（HSV-1）DNA。巨细胞病毒、水痘-带状疱疹病毒和人类疱疹病毒6型（HHV-6）DNA在3例患者（3%）中均被检测到；2型单纯疱疹病毒（HSV-2）和HHV-7的聚合酶链反应（PCR）结果为阴性。HSV检测与癫痫发作相关（P = 0.02），尤其是局灶性癫痫发作（P = 0.0002），以及与有局灶性病变的病理计算机断层扫描（P = 0.02）相关（P = 0.0004）。

相似文献

1
Prevalence of herpes simplex virus (types 1 and 2), varicella-zoster virus, cytomegalovirus, and human herpesvirus 6 and 7 DNA in cerebrospinal fluid of Middle Eastern patients with encephalitis.中东脑炎患者脑脊液中单纯疱疹病毒（1型和2型）、水痘-带状疱疹病毒、巨细胞病毒以及人类疱疹病毒6型和7型DNA的流行情况
J Clin Microbiol. 2005 Aug;43(8):4172-4. doi: 10.1128/JCM.43.8.4172-4174.2005.
2
Prevalence of human herpes virus types 1-7 in the semen of men attending an infertility clinic and correlation with semen parameters.就诊于不孕不育诊所男性精液中1-7型人类疱疹病毒的流行情况及其与精液参数的相关性。
Fertil Steril. 2009 Jun;91(6):2487-94. doi: 10.1016/j.fertnstert.2008.03.074. Epub 2008 Jun 18.
3
Detection of herpes simplex virus (1 and 2), varicella-zoster virus, cytomegalovirus, human herpesvirus 6 and enterovirus in immunocompetent Tunisian patients with acute neuromeningeal disorder.检测免疫功能正常的突尼斯急性神经脑膜障碍患者中的单纯疱疹病毒（1 型和 2 型）、水痘-带状疱疹病毒、巨细胞病毒、人类疱疹病毒 6 和肠道病毒。
J Med Virol. 2012 Feb;84(2):282-9. doi: 10.1002/jmv.23192.
4
Detection of both herpes simplex and varicella-zoster viruses in cerebrospinal fluid from patients with encephalitis.在脑炎患者脑脊液中检测单纯疱疹病毒和水痘-带状疱疹病毒。
J Med Virol. 1996 Sep;50(1):82-92. doi: 10.1002/(SICI)1096-9071(199609)50:1<82::AID-JMV14>3.0.CO;2-#.
5
Detection of herpesvirus DNA in cerebrospinal fluid and correlation with clinical symptoms.脑脊液中疱疹病毒DNA的检测及其与临床症状的相关性。
Infection. 2008 Mar;36(2):158-62. doi: 10.1007/s15010-007-6354-y. Epub 2008 Mar 31.
6
Prevalence of herpesviridae and hepatitis B virus DNA in the liver of patients with non-A, non-B fulminant hepatic failure.非甲非乙型暴发性肝衰竭患者肝脏中疱疹病毒科和乙型肝炎病毒DNA的流行情况。
Hepatology. 1996 Dec;24(6):1361-5. doi: 10.1002/hep.510240608.
7
The quantitative detection of herpes simplex virus, varicella zoster virus, and cytomegalovirus DNAs in recipient corneal buttons.受者角膜中的单纯疱疹病毒、水痘带状疱疹病毒和巨细胞病毒 DNA 的定量检测。
Cornea. 2010 Dec;29(12):1436-9. doi: 10.1097/ICO.0b013e3181d3d69d.
8
Automated detection of five human herpes virus DNAs by a set of LightCycler PCRs complemented with a single multiple internal control.通过一组LightCycler PCR并辅以单个多重内部对照自动检测五种人类疱疹病毒DNA。
J Clin Virol. 2004 Mar;29(3):171-8. doi: 10.1016/S1386-6532(03)00121-5.
9
Detection of lymphotropic herpesvirus DNA by polymerase chain reaction in cerebrospinal fluid of AIDS patients with neurological disease.通过聚合酶链反应检测患有神经疾病的艾滋病患者脑脊液中的嗜淋巴细胞疱疹病毒DNA。
Acta Virol. 2000 Jun-Aug;44(3):137-43.
10
Detection of herpes viruses in children with acute appendicitis.急性阑尾炎患儿中疱疹病毒的检测
J Clin Virol. 2009 Apr;44(4):282-6. doi: 10.1016/j.jcv.2009.01.013. Epub 2009 Feb 23.

引用本文的文献

1
CNS Viral Infections-What to Consider for Improving Drug Treatment: A Plea for Using Mathematical Modeling Approaches.中枢神经系统病毒感染——改善药物治疗需要考虑的因素：呼吁采用数学建模方法。
CNS Drugs. 2024 May;38(5):349-373. doi: 10.1007/s40263-024-01082-3. Epub 2024 Apr 5.
2
The Worldwide Prevalence of Herpes Simplex Virus Encephalitis and Meningitis: A Systematic Review and Meta-Analysis.单纯疱疹病毒性脑炎和脑膜炎的全球患病率：一项系统评价和荟萃分析。
Turk Arch Pediatr. 2023 Nov;58(6):580-587. doi: 10.5152/TurkArchPediatr.2023.23007.
3
Prevalence of types 1 and 2 infections among suspected children of encephalitis in Kermanshah, Iran.伊朗克尔曼沙赫疑似脑炎儿童中1型和2型感染的患病率。
Iran J Microbiol. 2023 Feb;15(1):149-154. doi: 10.18502/ijm.v15i1.11931.
4
Human herpes virus type-6 is associated with central nervous system infections in children in Sudan.人类疱疹病毒6型与苏丹儿童的中枢神经系统感染有关。
Afr J Lab Med. 2022 Sep 22;11(1):1718. doi: 10.4102/ajlm.v11i1.1718. eCollection 2022.
5
Detection of human herpesviruses in cerebrospinal fluids collected from patients suspected of neuroinfectious diseases.检测疑似神经感染性疾病患者脑脊液中的人类疱疹病毒。
J Neurovirol. 2022 Feb;28(1):92-98. doi: 10.1007/s13365-021-01040-5. Epub 2021 Dec 30.
6
Prevalence and clinical manifestations of herpes simplex virus infection among suspected patients of herpes simplex encephalitis in Shiraz, Iran.伊朗设拉子疑似单纯疱疹性脑炎患者中单纯疱疹病毒感染的患病率及临床表现
Virusdisease. 2021 Jun;32(2):266-271. doi: 10.1007/s13337-021-00680-9. Epub 2021 May 20.
7
Human Herpesviruses 6A and 6B in Brain Diseases: Association versus Causation.人类疱疹病毒 6A 和 6B 与脑部疾病：关联与因果关系。
Clin Microbiol Rev. 2020 Nov 11;34(1). doi: 10.1128/CMR.00143-20. Print 2020 Dec 16.
8
4-Hydroxy-2-quinolones 139. Synthesis, structure, and antiviral activity of N-R-amides of 2-hydroxy-4-oxo-4H-pyrido[1,2-]pyrimidine-3-carboxylic acids.4-羟基-2-喹诺酮139。2-羟基-4-氧代-4H-吡啶并[1,2-]嘧啶-3-羧酸N-R-酰胺的合成、结构及抗病毒活性
Chem Heterocycl Compd (N Y). 2008;44(1):50. doi: 10.1007/s10593-008-0012-x. Epub 2008 May 31.
9
Syndrome Evaluation System for Simultaneous Detection Pathogens Causing Acute Encephalitic Syndrome in India, Part-1: Development and Standardization of the Assay.印度急性脑炎综合征同时检测病原体的综合征评估系统，第1部分：检测方法的开发与标准化
Front Med (Lausanne). 2018 Jul 26;5:208. doi: 10.3389/fmed.2018.00208. eCollection 2018.
10
Roseolovirus-associated encephalitis in immunocompetent and immunocompromised individuals.免疫功能正常和免疫功能低下个体中的玫瑰疹病毒相关性脑炎。
J Neurovirol. 2017 Feb;23(1):1-19. doi: 10.1007/s13365-016-0473-0. Epub 2016 Aug 18.

本文引用的文献

1
Factors influencing PCR detection of viruses in cerebrospinal fluid of patients with suspected CNS infections.影响疑似中枢神经系统感染患者脑脊液中病毒PCR检测的因素。
J Neurol Neurosurg Psychiatry. 2005 Jan;76(1):82-7. doi: 10.1136/jnnp.2004.045336.
2
Detection of herpes simplex virus, cytomegalovirus and Epstein-Barr virus DNA in atherosclerotic plaques and in unaffected bypass grafts.在动脉粥样硬化斑块和未受影响的搭桥移植物中检测单纯疱疹病毒、巨细胞病毒和EB病毒DNA。
J Clin Virol. 2005 Jan;32(1):29-32. doi: 10.1016/j.jcv.2004.06.010.
3
High frequency of human herpesvirus 6 DNA in multiple sclerosis plaques isolated by laser microdissection.通过激光显微切割分离的多发性硬化斑块中人类疱疹病毒6型DNA的高频率。
J Infect Dis. 2003 May 1;187(9):1377-87. doi: 10.1086/368166. Epub 2003 Apr 9.
4
Outcome of and prognostic factors for herpes simplex encephalitis in adult patients: results of a multicenter study.成年患者单纯疱疹病毒性脑炎的结局及预后因素：一项多中心研究结果
Clin Infect Dis. 2002 Aug 1;35(3):254-60. doi: 10.1086/341405. Epub 2002 Jul 10.
5
Viral encephalitis: familiar infections and emerging pathogens.病毒性脑炎：常见感染与新出现的病原体
Lancet. 2002 Feb 9;359(9305):507-13. doi: 10.1016/S0140-6736(02)07681-X.
6
Frequency of herpes simplex virus in Syria based on type-specific serological assay.基于型特异性血清学检测的叙利亚单纯疱疹病毒感染率
Saudi Med J. 2000 Apr;21(4):355-60.
7
Acute viral encephalitis in adults--a prospective study.成人急性病毒性脑炎——一项前瞻性研究。
Scand J Infect Dis. 1998;30(3):215-20. doi: 10.1080/00365549850160828.
8
Application of competitive PCR to cerebrospinal fluid samples from patients with herpes simplex encephalitis.竞争性聚合酶链反应在单纯疱疹性脑炎患者脑脊液样本中的应用。
J Clin Microbiol. 1998 Aug;36(8):2229-34. doi: 10.1128/JCM.36.8.2229-2234.1998.
9
Etiology of acute childhood encephalitis at The Hospital for Sick Children, Toronto, 1994-1995.1994 - 1995年多伦多病童医院儿童急性脑炎的病因
Clin Infect Dis. 1998 Feb;26(2):398-409. doi: 10.1086/516301.
10
Human herpesvirus 6 is associated with focal encephalitis.人类疱疹病毒6型与局灶性脑炎有关。
Clin Infect Dis. 1995 Sep;21(3):571-6. doi: 10.1093/clinids/21.3.571.