de Jong Menno D, Hien Tran Tinh
Oxford University Clinical Research Unit, Hospital for Tropical Diseases, 190 Ben Ham Tu, District 5, Ho Chi Minh City, Viet Nam.
J Clin Virol. 2006 Jan;35(1):2-13. doi: 10.1016/j.jcv.2005.09.002. Epub 2005 Oct 6.
Since their reemergence in 2003, highly pathogenic avian influenza A (H5N1) viruses have reached endemic levels among poultry in several southeast Asian countries and have caused a still increasing number of more than 100 reported human infections with high mortality. These developments have ignited global fears of an imminent influenza pandemic. The current knowledge of the virology, clinical spectrum, diagnosis and treatment of human influenza H5N1 virus infections is reviewed herein.
自2003年高致病性甲型禽流感(H5N1)病毒再次出现以来,已在几个东南亚国家的家禽中达到地方流行程度,并已导致报告的人类感染病例数量仍在增加,超过100例,且死亡率很高。这些情况引发了全球对即将到来的流感大流行的担忧。本文综述了目前关于人类H5N1病毒感染的病毒学、临床症状、诊断和治疗的知识。