单纯疱疹病毒抗原对人淋巴细胞的刺激作用。
Stimulation of human lymphocytes by Herpes simplex virus antigens.
作者信息
Starr S E, Karatela S A, Shore S L, Duffey A, Nahmias A J
出版信息
Infect Immun. 1975 Jan;11(1):109-12. doi: 10.1128/iai.11.1.109-112.1975.
Abstract
Lymphocytes from individuals with laboratory evidence of prior infection with herpes simplex virus (HSV) type 1 or type 2 demonstrated transformation (av antigens. Higher stimulation indexes were obtained when lymphocytes were incubated with the homologous as compared with the heterologous antigen. Higher mean lymphocyte stimulation indexes were also demonstrated in seropositive as compared with seronegative individuals. Lymphocytes from children with HSV-1 stomatitis usually became responsive to HSV-1 antigen within 2 to 6 weeks after the onset of illness. Lymphocytes from infants with neonatal HSV-2 infection were stimulated by HSV-2 antigen.
摘要
来自有1型或2型单纯疱疹病毒（HSV）既往感染实验室证据个体的淋巴细胞表现出转化（针对抗原）。与异源抗原相比，淋巴细胞与同源抗原孵育时获得更高的刺激指数。血清阳性个体与血清阴性个体相比也表现出更高的平均淋巴细胞刺激指数。患有HSV-1口腔炎儿童的淋巴细胞通常在疾病发作后2至6周内对HSV-1抗原产生反应。患有新生儿HSV-2感染婴儿的淋巴细胞受到HSV-2抗原的刺激。
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本文引用的文献
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Cell-mediated immunity in Herpesvirus hominis infections.人疱疹病毒感染中的细胞介导免疫。
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Lymphocyte interferon production and transformation after Herpes simplex infections in humans.人类单纯疱疹感染后淋巴细胞干扰素的产生及转化
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