人类肿瘤坏死因子受体基因的染色体定位。

Chromosomal location of the human tumor necrosis factor receptor genes.

作者信息

Baker E, Chen L Z, Smith C A, Callen D F, Goodwin R, Sutherland G R

机构信息

Department of Cytogenetics and Molecular Genetics, Adelaide Children's Hospital, North Adelaide, Australia.

出版信息

Cytogenet Cell Genet. 1991;57(2-3):117-8. doi: 10.1159/000133127.

DOI:10.1159/000133127

PMID:1655358

Abstract

TNFR1 and TNFR2, the genes encoding the two forms of the human tumor necrosis factor receptor, were localized to normal human chromosomes by in situ hybridization and Southern blot analysis of a series of human x mouse hybrid cell lines. TNFR1 maps to 12p13 and TNFR2 maps to 1p36.

摘要

通过对一系列人-鼠杂交细胞系进行原位杂交和Southern印迹分析，编码两种形式人类肿瘤坏死因子受体的基因TNFR1和TNFR2被定位到正常人类染色体上。TNFR1定位于12p13，TNFR2定位于1p36。