乙型肝炎病毒（HBV）和丙型肝炎病毒（HCV）双重感染。
Hepatitis B virus (HBV) and hepatitis C virus (HCV) dual infection.
作者信息
Liu Zhihua, Hou Jinlin
机构信息
Department of Infectious Diseases and Hepatology Unit, Nanfang Hospital, Southern Medical University, Guangzhou, China.
出版信息
Int J Med Sci. 2006;3(2):57-62. doi: 10.7150/ijms.3.57. Epub 2006 Apr 1.
Abstract
Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections account for a substantial proportion of liver diseases worldwide. Because the two hepatotropic viruses share same modes of transmission, coinfection with the two viruses is not uncommon, especially in areas with a high prevalence of HBV infection and among people at high risk for parenteral infection. Patients with dual HBV and HCV infection have more severe liver disease, and are at an increased risk for progression to hepatocellular carcinoma (HCC). Treatment of viral hepatitis due to dual HBV/HCV infection represents a challenge.
摘要
乙型肝炎病毒（HBV）和丙型肝炎病毒（HCV）感染在全球范围内的肝脏疾病中占相当大的比例。由于这两种嗜肝病毒具有相同的传播方式，两种病毒合并感染并不罕见，尤其是在HBV感染高发地区以及经皮感染风险较高的人群中。HBV和HCV双重感染的患者肝脏疾病更为严重，进展为肝细胞癌（HCC）的风险也更高。治疗HBV/HCV双重感染所致的病毒性肝炎是一项挑战。
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