Barnard K D, Skinner T C, Peveler R
University of Southampton, UK.
Diabet Med. 2006 Apr;23(4):445-8. doi: 10.1111/j.1464-5491.2006.01814.x.
To review the literature estimating the cross-sectional prevalence of clinical depression in adults with Type 1 diabetes.
Electronic databases and published references were used to identify studies published between January 2000 and June 2004, with a previous meta-analysis used to identify studies before 1 January 2000.
Between January 2000 and June 2004, a further five eligible studies were identified. Only one was a controlled study using diagnostic interviewing to determine rates of depression. Taking all of the eligible studies identified by the previous meta-analysis and this search, the prevalence of clinical depression in controlled studies was 12.0% for people with diabetes compared with 3.2% for control subjects. In studies with no control group, the prevalence of clinical depression was 13.4%.
There are wide-ranging differences reported in the various studies on the prevalence of depression in Type 1 diabetes. In view of the differing methods of diagnosis and small participant numbers, the results should be viewed with caution. A controlled study using diagnostic interviewing techniques to determine levels of depression is recommended to provide a clearer picture of both the prevalence and characteristics of that depression.
回顾估算1型糖尿病成年患者临床抑郁症横断面患病率的文献。
利用电子数据库和已发表的参考文献来识别2000年1月至2004年6月期间发表的研究，此前的一项荟萃分析用于识别2000年1月1日前的研究。
在2000年1月至2004年6月期间，又识别出五项符合条件的研究。只有一项是采用诊断性访谈来确定抑郁症发病率的对照研究。综合此前荟萃分析及本次检索所识别出的所有符合条件的研究，对照研究中糖尿病患者临床抑郁症的患病率为12.0%，而对照受试者为3.2%。在无对照组的研究中，临床抑郁症的患病率为13.4%。
各项研究报告的1型糖尿病患者抑郁症患病率存在很大差异。鉴于诊断方法不同且参与人数较少，对结果应谨慎看待。建议采用诊断性访谈技术的对照研究来确定抑郁症水平，以便更清楚地了解该抑郁症的患病率及特征。
