Pircher Michael, Baumann Bernhard, Götzinger Erich, Hitzenberger Christoph K
Center for Biomedical Engineering and Physics, Medical University of Vienna, Währinger Strasse 13, A-1090 Vienna, Austria.
Opt Lett. 2006 Jun 15;31(12):1821-3. doi: 10.1364/ol.31.001821.
We improved our recently reported retinal OCT system based on transverse priority scanning to achieve high resolution in both the transverse and the axial directions. The implementation of an additional SLO channel enables precise on-line focusing. The system enables imaging of the human retinal cone mosaic off the foveal center without adaptive optics. We demonstrate, for what is believed to be the first time, cone mosaic imaging simultaneously in the scanning laser ophthalmoscope and optical coherence tomography (OCT) channels. OCT B-scan images demonstrate that the cone mosaic is observable in two adjacent layers. Furthermore, we present what are believed to be the first C-scan OCT images of the cone mosaic and show that the major part of light backscattered from below the photoreceptor layer is not guided back toward the pupil by the photoreceptors.
我们改进了我们最近报道的基于横向优先扫描的视网膜光学相干断层扫描（OCT）系统，以在横向和轴向方向上均实现高分辨率。增加一个扫描激光眼底镜（SLO）通道可实现精确的在线聚焦。该系统无需自适应光学器件即可对中央凹中心以外的人眼视网膜视锥细胞镶嵌进行成像。据我们所知，我们首次展示了在扫描激光眼底镜和光学相干断层扫描（OCT）通道中同时进行视锥细胞镶嵌成像。OCT B 扫描图像表明，视锥细胞镶嵌在相邻的两层中是可观察到的。此外，我们展示了据信是视锥细胞镶嵌的首批C扫描OCT图像，并表明从光感受器层下方反向散射的大部分光不会被光感受器引导回瞳孔。
