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在邻国马来西亚和新加坡的亚洲儿童中,屈光不正的特定种族患病率有所不同。

Ethnicity-specific prevalences of refractive errors vary in Asian children in neighbouring Malaysia and Singapore.

作者信息

Saw S-M, Goh P-P, Cheng A, Shankar A, Tan D T H, Ellwein L B

机构信息

Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore, Singapore.

出版信息

Br J Ophthalmol. 2006 Oct;90(10):1230-5. doi: 10.1136/bjo.2006.093450. Epub 2006 Jun 29.

Abstract

AIM

To compare the prevalences of refractive errors in Malay, Chinese and Indian children in Malaysia and Singapore.

METHODS

Children aged 7-9 years from three schools in the Singapore Cohort study of the Risk factors for Myopia (n = 1962) and similarly aged children from a random cluster sample in the metropolitan Kuala Lumpur area in the Malaysia Refractive Error Study in Children (n = 1752) were compared. Cycloplegic autorefraction was conducted in both countries.

RESULTS

The prevalence of myopia (spherical equivalent of at least -0.5 diopters (D) in either eye) was higher in Singapore Malays (22.1%) than in Malays in Malaysia (9.2%; 95% confidence interval (CI) 11.2 to 14.7; p<0.001). Similarly, Singapore Chinese (40.1%) had higher prevalences than Malaysian Chinese (30.9%; 95% CI 1.5 to 16.9). Singapore Indians had a higher prevalence (34.1%) than Malaysian Indians (12.5%; 95% CI 17.4 to 25.9). The multivariate odds ratio of astigmatism (cylinder at least 0.75 D in either eye) in Singapore Malays compared with Malaysian Malays was 3.47 (95% CI 2.79 to 4.32). Ethnicity-specific hyperopia rates did not differ in Singapore and Malaysia.

CONCLUSION

The ethnicity-specific prevalences of myopia in Singapore Malays, Chinese and Indians are higher than those in Malaysian Malays, Chinese and Indians. As Malays, Chinese and Indians in Malaysia have genetic make-up similar to that of Malays, Chinese and Indians in Singapore, environmental factors may contribute to the higher myopia rates.

摘要

目的

比较马来西亚和新加坡马来族、华裔和印度裔儿童屈光不正的患病率。

方法

对新加坡近视危险因素队列研究中三所学校7至9岁的儿童(n = 1962)以及马来西亚儿童屈光不正研究中吉隆坡都会区随机整群抽样的同龄儿童(n = 1752)进行比较。两国均进行了睫状肌麻痹验光。

结果

新加坡马来族儿童近视(任何一只眼睛等效球镜度数至少为-0.50屈光度(D))的患病率(22.1%)高于马来西亚马来族儿童(9.2%;95%置信区间(CI)为11.2至14.7;p<0.001)。同样,新加坡华裔儿童(40.1%)的患病率高于马来西亚华裔儿童(30.9%;95%CI为1.5至16.9)。新加坡印度裔儿童的患病率(34.1%)高于马来西亚印度裔儿童(12.5%;95%CI为17.4至25.9)。与马来西亚马来族儿童相比,新加坡马来族儿童散光(任何一只眼睛柱镜度数至少为0.75 D)的多变量优势比为3.47(95%CI为2.79至4.32)。新加坡和马来西亚特定族裔的远视率没有差异。

结论

新加坡马来族、华裔和印度裔儿童近视的特定族裔患病率高于马来西亚的马来族、华裔和印度裔儿童。由于马来西亚的马来族、华裔和印度裔与新加坡的马来族、华裔和印度裔具有相似的基因构成,环境因素可能导致了更高近视率。

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