Villarruel Antonia M, Jemmott John B, Jemmott Loretta S
School of Nursing, University of Michigan, Ann Arbor, MI 48109-0482, USA.
Arch Pediatr Adolesc Med. 2006 Aug;160(8):772-7. doi: 10.1001/archpedi.160.8.772.
To test the efficacy of a prevention intervention to reduce sexual risk behavior among Latino adolescents.
Randomized controlled trial from April 2000 through March 2003, with data collection before and after intervention and at 3, 6, and 12 months.
Northeast Philadelphia schools.
Latinos aged 13 through 18 years (249 males and 304 females); 81.6% retained at 12-month follow-up.
The HIV and health-promotion control interventions consisted of six 50-minute modules delivered by adult facilitators to small, mixed-gender groups in English or Spanish. Main Outcome Measure Self-reported sexual behavior.
Analyses using generalized estimation equations over the follow-up period revealed that adolescents in the HIV intervention were less likely to report sexual intercourse (odds ratio, 0.66; 95% confidence interval [CI], 0.46-0.96), multiple partners (odds ratio, 0.53; 95% CI, 0.31-0.90), and days of unprotected intercourse (relative risk, 0.47; 95% CI, 0.26-0.84) and more likely to report using condoms consistently (odds ratio, 1.91; 95% CI, 1.24-2.93). Baseline sexual experience and language use moderated intervention efficacy. Adolescents assigned to the HIV intervention who were sexually inexperienced at baseline reported fewer days of unprotected sex (relative risk, 0.22; 95% CI, 0.08-0.63); Spanish speakers were more likely to have used a condom at last intercourse (odds ratio, 4.73; 95% CI, 1.72-12.97) and had a greater proportion of protected sex (mean difference, 0.35; P<.01) compared with similar adolescents in the health-promotion intervention.
Results provide evidence for the efficacy of HIV intervention in decreasing sexual activity and increasing condom use among Latino adolescents.
测试一项预防干预措施在降低拉丁裔青少年性风险行为方面的效果。
2000年4月至2003年3月的随机对照试验，在干预前后以及3个月、6个月和12个月时收集数据。
费城东北部学校。
年龄在13至18岁的拉丁裔（249名男性和304名女性）；12个月随访时的保留率为81.6%。
艾滋病毒和健康促进对照干预措施包括由成年辅导员向男女混合的小组用英语或西班牙语讲授的六个50分钟的单元。主要结局指标为自我报告的性行为。
在随访期间使用广义估计方程进行的分析显示，接受艾滋病毒干预的青少年报告性交的可能性较小（优势比，0.66；95%置信区间[CI]，0.46 - 0.96）、有多个性伴侣的可能性较小（优势比，0.53；95%CI，0.31 - 0.90）以及无保护性交天数较少（相对风险，0.47；95%CI，0.26 - 0.84），并且更有可能报告始终使用避孕套（优势比，1.91；95%CI，1.24 - 2.93）。基线性经历和语言使用对干预效果有调节作用。在基线时没有性经历的接受艾滋病毒干预的青少年报告的无保护性行为天数较少（相对风险，0.22；95%CI，0.08 - 0.63）；与健康促进干预中类似的青少年相比，说西班牙语的青少年在最后一次性交时更有可能使用避孕套（优势比，4.73；95%CI，1.72 - 12.97），并且有更高比例的受保护性行为（平均差异，0.35；P <.01）。
结果为艾滋病毒干预在减少拉丁裔青少年性活动和增加避孕套使用方面的效果提供了证据。
