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人类免疫缺陷病毒与丙型肝炎和乙型肝炎的合并感染。

HIV coinfection with hepatitis C and hepatitis B.

作者信息

Smith Jenny O, Sterling Richard K

机构信息

Section of Hepatology, Virginia Commonwealth University Medical Center, 1200 E Broad Street, Room 1492, Box 908341, Richmond, VA 23298-0341, USA.

出版信息

Curr Infect Dis Rep. 2006 Sep;8(5):409-18. doi: 10.1007/s11908-006-0053-1.

Abstract

HIV, hepatitis C virus, and hepatitis B virus are global health concerns. Due to shared routes of transmission, coinfection is common. The incidence of liver-related mortality in coinfected patients has risen significantly since the inception of highly active antiretroviral therapy, a treatment that has helped decreased mortality rates from AIDS and opportunistic infections. This trend has led to increased research into the evaluation and management of the coinfected patient. This article details the principles of successful management of this challenging patient population.

摘要

人类免疫缺陷病毒(HIV)、丙型肝炎病毒和乙型肝炎病毒是全球关注的健康问题。由于传播途径相同,合并感染很常见。自从高效抗逆转录病毒治疗开始以来,合并感染患者中与肝脏相关的死亡率显著上升,这种治疗有助于降低艾滋病和机会性感染的死亡率。这一趋势导致了对合并感染患者评估和管理的研究增加。本文详细介绍了成功管理这一具有挑战性患者群体的原则。

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