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人类免疫缺陷病毒与丙型肝炎和乙型肝炎的合并感染。

HIV coinfection with hepatitis C and hepatitis B.

作者信息

Smith Jenny O, Sterling Richard K

机构信息

Section of Hepatology, Virginia Commonwealth University Medical Center, 1200 E Broad Street, Room 1492, Box 908341, Richmond, VA 23298-0341, USA.

出版信息

Curr Infect Dis Rep. 2006 Sep;8(5):409-18. doi: 10.1007/s11908-006-0053-1.

DOI:10.1007/s11908-006-0053-1
PMID:16934201
Abstract

HIV, hepatitis C virus, and hepatitis B virus are global health concerns. Due to shared routes of transmission, coinfection is common. The incidence of liver-related mortality in coinfected patients has risen significantly since the inception of highly active antiretroviral therapy, a treatment that has helped decreased mortality rates from AIDS and opportunistic infections. This trend has led to increased research into the evaluation and management of the coinfected patient. This article details the principles of successful management of this challenging patient population.

摘要

人类免疫缺陷病毒(HIV)、丙型肝炎病毒和乙型肝炎病毒是全球关注的健康问题。由于传播途径相同,合并感染很常见。自从高效抗逆转录病毒治疗开始以来,合并感染患者中与肝脏相关的死亡率显著上升,这种治疗有助于降低艾滋病和机会性感染的死亡率。这一趋势导致了对合并感染患者评估和管理的研究增加。本文详细介绍了成功管理这一具有挑战性患者群体的原则。

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本文引用的文献

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Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection.开发一种简单的非侵入性指标以预测HIV/HCV合并感染患者的显著纤维化。
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替诺福韦酯对HIV感染患者的抗乙型肝炎病毒疗效
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Hepatitis B or hepatitis C and human immunodeficiency virus infection.乙型肝炎或丙型肝炎与人类免疫缺陷病毒感染。
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Role of liver biopsy in the evaluation of hepatitis C virus infection in HIV coinfection.肝活检在评估合并感染人类免疫缺陷病毒的丙型肝炎病毒感染中的作用。
Clin Infect Dis. 2005 Apr 15;40 Suppl 5:S270-5. doi: 10.1086/427439.