艾滋病毒与丙型肝炎病毒合并感染
HIV-HCV Coinfection.
作者信息
Sethi Amrita, Sterling Richard K
机构信息
Dr. Sethi is a Senior Fellow in Hepatology and Dr. Sterling is Associate Professor of Medicine and Director of the HIV-Liver Disease Clinic, both in the Division of Gastroenterology, Hepatology, and Nutrition of the Virginia Commonwealth University Health System, Richmond, Va.
出版信息
Gastroenterol Hepatol (N Y). 2006 May;2(5):357-365.
Human immunodeficiency virus and hepatitis C virus are global health concerns. Due to shared routes of transmission, coinfection is common. Since the introduction of highly active antiretroviral therapy in the mid-1990s and the associated marked reduction in HIV-related mortality, the incidence of liver-related mortality in coinfected patients has risen significantly. This rise has led to increased research into the evaluation and management of the coinfected patient. This article reviews the epidemiology and evaluation of the coinfected patient and outlines the principles necessary for successful management of this challenging patient population.
人类免疫缺陷病毒和丙型肝炎病毒是全球卫生关注的重点。由于传播途径相同，合并感染很常见。自20世纪90年代中期引入高效抗逆转录病毒疗法以及与之相关的HIV相关死亡率显著降低以来，合并感染患者肝脏相关死亡率的发生率已显著上升。这种上升导致了对合并感染患者评估和管理的研究增加。本文综述了合并感染患者的流行病学和评估，并概述了成功管理这一具有挑战性的患者群体所需的原则。
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