Hosseini Seyed Vahid, Ghanbarzadeh Kurosh, Barzin Jahra, Sadjjadi Seyed Mahmoud, Tanideh Nader, Mehrabani Davood
Department of Surgery, Gastroenterohepatology Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Korean J Parasitol. 2006 Sep;44(3):239-42. doi: 10.3347/kjp.2006.44.3.239.
To evaluate the protoscolicidal effects of various concentrations of hypertonic glucose, live protoscolices of sheep were exposed to 10%, 15%, 25% and 50% glucose solutions. Cetrimide (0.5%), silver nitrate (0.5%) and hypertonic saline (20%) were used as positive controls, while physiological saline was used as a negative control. After 1, 2 and 5 min, the protoscolicidal effects were determined by 1% eosin. A 25% glucose solution had no significant protoscolicidal effect. However, a 50% glucose solution revealed higher protoscolicidal effect than 0.5% silver nitrate but weaker effect than 0.5% cetrimide; the effect was comparable with that of 20% hypertonic saline. The results showed that hypertonic glucose solution is highly effective in killing protoscolices of Echinococcus granulosus in vitro.
为评估不同浓度高渗葡萄糖的原头蚴杀灭效果，将绵羊的活原头蚴暴露于10%、15%、25%和50%的葡萄糖溶液中。使用西曲溴铵（0.5%）、硝酸银（0.5%）和高渗盐水（20%）作为阳性对照，而生理盐水用作阴性对照。在1、2和5分钟后，用1%伊红测定原头蚴杀灭效果。25%的葡萄糖溶液没有显著的原头蚴杀灭作用。然而，50%的葡萄糖溶液显示出比0.5%硝酸银更高的原头蚴杀灭效果，但比0.5%西曲溴铵的效果弱；其效果与20%高渗盐水相当。结果表明，高渗葡萄糖溶液在体外对细粒棘球绦虫原头蚴具有高效杀灭作用。
