Bodrumlu Emre, Semiz Mustafa
Conservative Dentistry and Endodontics Department, Faculty of Dentistry, Ondokuz Mayis University, 55139 Kurupelit-Samsun/Turkey.
J Can Dent Assoc. 2006 Sep;72(7):637.
The purpose of this study was to test a new root canal sealer (Epiphany) and 5 other root canal sealers (Diaket, Endomethasone, AH 26, Sealapex, Sultan) for their antimicrobial effect on Enterococcus faecalis.
The antimicrobial effect of 6 root canal sealers was tested by the agar diffusion method. The freshly mixed sealers were placed in prepared wells of agar plates inoculated with E. faecalis. All plates were incubated for 72 hours at 37 degrees C under aerobic conditions, and zones of inhibition were measured at 24, 48 and 72 hours.
All of the sealers caused bacterial growth inhibition. Their effectiveness, in descending order of antimicrobial activity, was as follows: Endomethasone, Sultan, Sealapex, Diaket, Epiphany and AH 26. Epiphany sealer had little effect on the tested microorganism. The effectiveness of the root canal sealers decreased marginally with greater duration of incubation.
The Epiphany root canal sealer offered no antibacterial advantage over the other sealers tested.
本研究旨在测试一种新型根管封闭剂（Epiphany）以及其他5种根管封闭剂（Diaket、Endomethasone、AH 26、Sealapex、Sultan）对粪肠球菌的抗菌效果。
采用琼脂扩散法测试6种根管封闭剂的抗菌效果。将新鲜混合的封闭剂置于接种了粪肠球菌的琼脂平板的制备孔中。所有平板在37℃有氧条件下孵育72小时，并在24、48和72小时测量抑菌圈。
所有封闭剂均能抑制细菌生长。其有效性按抗菌活性从高到低依次为：Endomethasone、Sultan、Sealapex、Diaket、Epiphany和AH 26。Epiphany封闭剂对受试微生物几乎没有作用。随着孵育时间延长，根管封闭剂的有效性略有下降。
与其他受试封闭剂相比，Epiphany根管封闭剂没有抗菌优势。
