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风险评估与食物过敏:应用于过敏原的概率模型

Risk assessment and food allergy: the probabilistic model applied to allergens.

作者信息

Spanjersberg M Q I, Kruizinga A G, Rennen M A J, Houben G F

机构信息

TNO Quality of Life, Department Food and Chemical Risk Assessment, Utrechtseweg 48, P.O. Box 360, 3704 HE Zeist, Netherlands.

出版信息

Food Chem Toxicol. 2007 Jan;45(1):49-54. doi: 10.1016/j.fct.2006.07.018. Epub 2006 Aug 10.

DOI:10.1016/j.fct.2006.07.018
PMID:16979276
Abstract

In order to assess the risk of unintended exposure to food allergens, traditional deterministic risk assessment is usually applied, leading to inconsequential conclusions as 'an allergic reaction cannot be excluded'. TNO therefore developed a quantitative risk assessment model for allergens based on probabilistic techniques resulting in a more exhaustive risk assessment and more detailed information. By now, this approach is recognized as the future approach in allergen risk assessment. A case study (hazelnut proteins in chocolate spread) is presented as a proof of concept.

摘要

为了评估意外接触食物过敏原的风险,通常采用传统的确定性风险评估方法,得出的结论往往无关紧要,如“不能排除过敏反应”。因此,荷兰应用科学研究院(TNO)基于概率技术开发了一种过敏原定量风险评估模型,从而实现更详尽的风险评估和更详细的信息。目前,这种方法被公认为是过敏原风险评估的未来发展方向。本文通过一个案例研究(巧克力酱中的榛子蛋白)来证明这一概念。

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