Mystakidou Kyriaki, Tsilika Eleni, Parpa Efi, Galanos Antonis, Vlahos Lambros
Pain Relief and Palliative Care Unit, Department of Radiology, Areteion Hospital, School of Medicine, University of Athens, 27 Korinthias Street, 115 26 Athens, Greece.
Psychooncology. 2007 Apr;16(4):352-7. doi: 10.1002/pon.1090.
The aim of the present study was to validate the Greek version of the MMSE in advanced-cancer patients attending a palliative care unit.
The sample consisted of 103 advanced-cancer patients. The questionnaire was completed at baseline and three days later. Together with the MMSE, the patients also completed the EORTC QLQ-C30 Cognitive functioning scale, while researchers recorded data on demographic characteristics, disease status and treatment regimen.
MMSE had overall Cronbach alpha 0.890. Validity as performed using known-group analysis showed good results. MMSE discriminated well between subgroups of patients differing in disease severity as defined by ECOG performance status. Comparison between the MMSE and the EORTC Cognitive functioning scale was statistically significant (p<0.05).
These psychometric properties of the Greek version of the MMSE confirm it as a valid and reliable measure when administered to patients with advanced cancer.
本研究旨在验证简易精神状态检查表（MMSE）希腊语版本在姑息治疗病房的晚期癌症患者中的有效性。
样本包括103名晚期癌症患者。问卷在基线时和三天后完成。患者除完成MMSE外，还完成了欧洲癌症研究与治疗组织生活质量问卷核心30项（EORTC QLQ-C30）认知功能量表，同时研究人员记录了人口统计学特征、疾病状态和治疗方案的数据。
MMSE的总体克朗巴哈系数为0.890。使用已知群体分析进行的效度检验显示出良好的结果。MMSE能够很好地区分根据东部肿瘤协作组（ECOG）体能状态定义的疾病严重程度不同的患者亚组。MMSE与EORTC认知功能量表之间的比较具有统计学意义（p<0.05）。
MMSE希腊语版本的这些心理测量特性证实，将其应用于晚期癌症患者时是一种有效且可靠的测量工具。
