艾滋病患者中与进行性多灶性白质脑病相关的免疫重建炎症综合征：一种可治疗的疾病。
Immune reconstitution inflammatory syndrome associated with PML in AIDS: a treatable disorder.
作者信息
Martinez J V, Mazziotti J V, Efron E D, Bonardo P, Jordan R, Sevlever G, Martinez M, Verbanaz S C, Salazar Z Salazar, Pardal M Fernandez, Reisin R
机构信息
Infectious Diseases Department, Hospital Británico, Buenos Aires, Argentina.
出版信息
Neurology. 2006 Nov 14;67(9):1692-4. doi: 10.1212/01.wnl.0000242728.26433.12.
An HIV-1-infected patient with progressive multifocal leukoencephalopathy presented clinical deterioration and contrast-enhancing lesions on brain nuclear MR after the initiation of highly active antiretroviral therapy (HAART). Brain biopsy identified an inflammatory reaction compatible with immune reconstitution inflammatory syndrome. Treatment with corticosteroids and transient suppression of HAART led to marked neurologic improvement.
一名患有进行性多灶性白质脑病的HIV-1感染患者在开始高效抗逆转录病毒治疗（HAART）后出现临床病情恶化及脑核磁共振成像（MRI）增强病灶。脑活检确定为与免疫重建炎症综合征相符的炎症反应。使用皮质类固醇治疗并短暂停用HAART后，患者神经功能显著改善。
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