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我的病人会摔倒吗?

Will my patient fall?

作者信息

Ganz David A, Bao Yeran, Shekelle Paul G, Rubenstein Laurence Z

机构信息

Veterans Affairs Greater Los Angeles Health Care System, Los Angeles, Calif 90073, USA.

出版信息

JAMA. 2007 Jan 3;297(1):77-86. doi: 10.1001/jama.297.1.77.

Abstract

CONTEXT

Effective multifactorial interventions reduce the frequent falling rate of older patients by 30% to 40%. However, clinical consensus suggests reserving these interventions for high-risk patients. Limiting fall prevention programs to high-risk patients implies that clinicians must recognize features that predict future falls.

OBJECTIVE

To identify the prognostic value of risk factors for future falls among older patients.

DATA SOURCES AND STUDY SELECTION

Search of MEDLINE (1966-September 2004), CINAHL (1982-September 2004), and authors' own files to identify prospective cohort studies of risk factors for falls that performed a multivariate analysis of such factors.

DATA EXTRACTION

Two reviewers independently determined inclusion of articles and assessed study quality. Disagreements were resolved by consensus. Included studies were those identifying the prognostic value of risk factors for future falls among community-dwelling persons 65 years and older. Clinically identifiable risk factors were identified across 6 domains: orthostatic hypotension, visual impairment, impairment of gait or balance, medication use, limitations in basic or instrumental activities of daily living, and cognitive impairment.

DATA SYNTHESIS

Eighteen studies met inclusion criteria and provided a multivariate analysis including at least 1 of the risk factor domains. The estimated pretest probability of falling at least once in any given year for individuals 65 years and older was 27% (95% confidence interval, 19%-36%). Patients who have fallen in the past year are more likely to fall again [likelihood ratio range, 2.3-2.8]. The most consistent predictors of future falls are clinically detected abnormalities of gait or balance (likelihood ratio range, 1.7-2.4). Visual impairment, medication variables, decreased activities of daily living, and impaired cognition did not consistently predict falls across studies. Orthostatic hypotension did not predict falls after controlling for other factors.

CONCLUSIONS

Screening for risk of falling during the clinical examination begins with determining if the patient has fallen in the past year. For patients who have not previously fallen, screening consists of an assessment of gait and balance. Patients who have fallen or who have a gait or balance problem are at higher risk of future falls.

摘要

背景

有效的多因素干预措施可使老年患者的频繁跌倒率降低30%至40%。然而,临床共识建议将这些干预措施保留给高危患者。将跌倒预防计划局限于高危患者意味着临床医生必须识别出预测未来跌倒的特征。

目的

确定老年患者未来跌倒风险因素的预后价值。

数据来源和研究选择

检索MEDLINE(1966年至2004年9月)、CINAHL(1982年至2004年9月)以及作者自己的资料,以识别对跌倒风险因素进行多因素分析的前瞻性队列研究。

数据提取

两名评审员独立确定文章的纳入情况并评估研究质量。分歧通过协商解决。纳入的研究是那些确定65岁及以上社区居住者未来跌倒风险因素的预后价值的研究。在6个领域确定了临床上可识别的风险因素:体位性低血压、视力障碍、步态或平衡受损、药物使用、基本或工具性日常生活活动受限以及认知障碍。

数据综合

18项研究符合纳入标准,并提供了包括至少1个风险因素领域的多因素分析。65岁及以上个体在任何给定年份至少跌倒一次的估计预测试概率为27%(95%置信区间,19%-36%)。过去一年中跌倒过的患者再次跌倒的可能性更大[似然比范围,2.3-2.8]。未来跌倒最一致的预测因素是临床上检测到的步态或平衡异常(似然比范围,1.7-2.4)。视力障碍、药物变量、日常生活活动减少和认知受损在各项研究中并非始终能预测跌倒。在控制其他因素后,体位性低血压不能预测跌倒。

结论

在临床检查中筛查跌倒风险首先要确定患者在过去一年中是否跌倒过。对于以前未跌倒过的患者,筛查包括评估步态和平衡。跌倒过或有步态或平衡问题的患者未来跌倒的风险更高。

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