念珠菌血流分离株形成的生物膜对棘白菌素类抗真菌药物敏感性的种属特异性差异。
Species-specific differences in the susceptibilities of biofilms formed by Candida bloodstream isolates to echinocandin antifungals.
作者信息
Choi Hyun Woo, Shin Jong Hee, Jung Sook In, Park Kyung Hwa, Cho Duck, Kee Seung Jung, Shin Myung Geun, Suh Soon Pal, Ryang Dong Wook
机构信息
Department of Laboratory Medicine, Chonnam National University Medical School, 8 Hakdong Dongku, Gwangju 501-757, South Korea.
出版信息
Antimicrob Agents Chemother. 2007 Apr;51(4):1520-3. doi: 10.1128/AAC.01141-06. Epub 2007 Feb 5.
Abstract
The echinocandin susceptibilities of bloodstream Candida isolates growing in a biofilm was investigated. Within the therapeutic range of concentrations of each drug, caspofungin and micafungin were active against biofilms formed by Candida albicans or C. glabrata but not those formed by C. tropicalis or C. parapsilosis.
摘要
对在生物膜中生长的血流念珠菌分离株的棘白菌素敏感性进行了研究。在每种药物的治疗浓度范围内，卡泊芬净和米卡芬净对白色念珠菌或光滑念珠菌形成的生物膜有活性，但对热带念珠菌或近平滑念珠菌形成的生物膜无活性。
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